Lttl vs SkinnyRx
In our scoring, SkinnyRx edges ahead overall (7.6 vs 7.2 out of 10), and Lttl costs less for compounded semaglutide (about $504 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Lttl $99/mo vs SkinnyRx $149.25/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $504 a year less with Lttl · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Included
- Lttl: medication, clinician visits, shipping; SkinnyRx: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: Lttl none, SkinnyRx 1

Lttl
Affiliate partnerBest for every commitment tier priced openly, plus a low-dose microdose option
semaglutide
$99
billed every 4 weeks
Our score 7.2/10

SkinnyRx
Affiliate partnerBest for compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
semaglutide
$149.25
Our score 7.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Lttl
SkinnyRx
Price
Semaglutide / month
Better on this row: $99/mo
billed every 4 weeks
$149.25/mo
Semaglutide / year (modeled)
Better on this row: $1,287
13 charges
$1,791
Tirzepatide / month
Better on this row: $149/mo
billed every 4 weeks
$224.25/mo
Tirzepatide / year (modeled)
Better on this row: $1,937
13 charges
$2,691
Oral semaglutide / month
Better on this row: $179/mo
$149 first month
$199/mo
Oral semaglutide / year (modeled)
Better on this row: $2,148
$2,388
Brand Wegovy / Ozempic / month
Not listed
$1,400/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,400/mo
Coverage
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
FSA/HSA accepted
Yes
Not listed
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
Cancel anytime
Yes
Not disclosed
Minimum commitment
None on the monthly plan; 3-, 6- and 12-month prepay tiers offered at lower per-month rates
Not disclosed
Refunds
Not disclosed
90-day money-back guarantee
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
October 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Lttl if…
- About $504 a year less than SkinnyRx for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- No FDA warning letters on record (SkinnyRx has 1)
- Accepts FSA/HSA cards
What to weigh up
- Partner pharmacies are never named — the site refers only to 'a partner U.S. pharmacy' (a material disclosure gap for a YMYL purchase)
- Headline 'Plans start at' prices ($89 semaglutide, $139 tirzepatide) are 12-month prepay rates; month-to-month is $99 and $149

Choose SkinnyRx if…
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which Lttl doesn't price
- Licensed US clinicians on every prescription
- Discreet shipping included; cancel anytime
What to weigh up
- 1 FDA warning letter on record
- About $504 a year more than Lttl for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Lttl
7.2/10
SkinnyRx
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Lttl vs SkinnyRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.