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Lttl vs PlexusDx

In our scoring, Lttl edges ahead overall (7.2 vs 7.0 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Lttl $99/mo billed every 4 weeks; PlexusDx $129/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
Coverage
PlexusDx 50 states (Lttl doesn't publish a state list)
Included
Lttl: medication, clinician visits, shipping; PlexusDx: medication, clinician visits

How we compare providers

Lttl logo

Lttl

Affiliate partner

Best for every commitment tier priced openly, plus a low-dose microdose option

semaglutide

$99/mo

billed every 4 weeks

Our score 7.2/10

PlexusDx logo

PlexusDx

Affiliate partner

Best for nationwide compounded GLP-1 with optional genetic-test personalization

semaglutide

$129/mo

microdose plan

Our score 7.0/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Lttl

PlexusDx

Price

Semaglutide / month

$99/mo

billed every 4 weeks

$129/mo

microdose plan

Semaglutide / year (modeled)

$1,287

13 charges

$1,548

Tirzepatide / month

$149/mo

billed every 4 weeks

$249/mo

starting dose

Tirzepatide / year (modeled)

$1,937

13 charges

$2,988

Oral semaglutide / month

$179/mo

$149 first month · microdose plan

Not listed

Coverage

State availability

List not published

50 states

Oral option listed

Yes

Not listed

Included in the price

Medication, clinician visits, shipping

Medication, clinician visits

FSA/HSA accepted

Yes

Not listed

Terms & safety

Price shown

Before intake

Before intake

Cancel anytime

Yes

Not disclosed

Minimum commitment

None on the monthly plan; 3-, 6- and 12-month prepay tiers offered at lower per-month rates

Not disclosed

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Every dose and plan: Lttl · PlexusDx

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Lttl logo

Choose Lttl if…

  • Lists oral compounded semaglutide, which PlexusDx doesn't price
  • Accepts FSA/HSA cards
  • Publishes the full price matrix — every medication, form and commitment length — on a public /plans page before checkout

What to weigh up

  • No published state list; confirm yours at signup
  • Partner pharmacies are never named — the site refers only to 'a partner U.S. pharmacy' (a material disclosure gap for a YMYL purchase)
PlexusDx logo

Choose PlexusDx if…

  • Publishes its full state list (50 states)
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform

What to weigh up

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Lttl

7.2/10

Overall

PlexusDx

7.0/10

Value25%

7.0A
vs
B
7.0

Effectiveness25%

7.5A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
6.8

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.0A
vs
B
6.5

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6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

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From $249/mo

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7.7

Ro

FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help

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From $149/mo (+ required membership)

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8.0

ShedRx

Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans

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From $299/mo (after intro offer)

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Lttl vs PlexusDx: FAQ

Lttl scores higher overall at 7.2/10 versus 7.0/10, and is particularly strong for every commitment tier priced openly, plus a low-dose microdose option. That said, PlexusDx is a better fit if you want nationwide compounded GLP-1 with optional genetic-test personalization.
Both Lttl and PlexusDx are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Lttl: $99 (billed every 4 weeks, 13 charges a year), about $1,287 a year. PlexusDx: $129, about $1,548 a year. Not like-for-like: one figure is a microdose plan.
Lttl doesn't publish a state list. PlexusDx publishes 50 states. Where a list isn't published, confirm your state during sign-up before paying.
Lttl: cancel anytime — yes; minimum commitment — None on the monthly plan; 3-, 6- and 12-month prepay tiers offered at lower per-month rates; early-cancellation fee — not disclosed. PlexusDx doesn't state its cancellation terms. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Lttl and PlexusDx head-to-heads in the same category.

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