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LeanDose vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
LeanDose logo

LeanDose

7.5
★★★3.8/5

Best for: Doctor-supervised compounded GLP-1 with transparent all-inclusive pricing

Visit LeanDose
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

LeanDose and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $159/mo, and NewSelf edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

LeanDose

First monthCompounded
$159/mo
semaglutide

Transparent first-month all-inclusive pricing from $159; ongoing monthly cost may differ. FDA-registered compounding pharmacy.

First monthCompounded
$279/mo
tirzepatide

Transparent first-month all-inclusive pricing from $279; ongoing monthly cost may differ.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

LeanDose

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

LeanDose

7.5/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.5A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.3

Accessibility10%

6.5A
vs
B
8.5

Support10%

7.9A
vs
B
7.9

Features & Coverage

FeatureLeanDoseNewSelf
Starting Price$159/mo$100/mo
Features8 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNone1 warning

About LeanDose

LeanDose is a doctor-guided compounded GLP-1 telehealth service for eligible adults, with transparent all-inclusive first-month pricing: compounded semaglutide from $159 and tirzepatide from $279. Treatment is doctor-prescribed and supervised, with personalized care plans, multi-state clinical support, and at-home delivery from an FDA-registered compounding pharmacy. It carries verifiable LegitScript certification and 119 five-star reviews. Compounded medications are not FDA-approved; ongoing pricing may differ from the first-month rate and the pharmacy is unnamed.

Read our full LeanDose review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

LeanDose

What we like

  • Transparent all-inclusive first-month pricing (compounded semaglutide from $159, tirzepatide from $279)
  • Verifiable LegitScript certification (seal ID 49840868) and an FDA-registered compounding pharmacy
  • Doctor-prescribed and supervised, with personalized care plans and multi-state clinical support
  • Convenient at-home delivery; compounded semaglutide and tirzepatide options
  • Honest, modest social proof — 119 five-star patient reviews

Watch-outs

  • Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
  • Headline rates are first-month pricing; your ongoing monthly cost may be higher
  • Available in multiple states but the full list is not published on the homepage
  • The compounding pharmacy is FDA-registered but not named

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out LeanDose with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. LeanDose remains a solid alternative, especially if you're looking for Doctor-supervised compounded GLP-1 with transparent all-inclusive pricing.

Choose LeanDose if…

You want Doctor-supervised compounded GLP-1 with transparent all-inclusive pricing and a starting price around $159/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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LeanDose vs NewSelf: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.