LeanDose vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
LeanDose
Best for: Doctor-supervised compounded semaglutide or tirzepatide with transparent all-inclusive pricing
Visit LeanDose →
Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →LeanDose and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $159/mo, and Amazon One Medical edges ahead overall (8.7 vs 8.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
LeanDose
Transparent first-month all-inclusive pricing from $159; ongoing monthly cost may differ. FDA-registered compounding pharmacy.
Transparent first-month all-inclusive pricing from $279; ongoing monthly cost may differ.
Amazon One Medical
What’s included
LeanDose
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
LeanDose
8.0/10
Amazon One Medical
8.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | LeanDose | Amazon One Medical |
|---|---|---|
| Starting Price | $159/mo | ✓$149/mo |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About LeanDose
LeanDose is a doctor-guided compounded GLP-1 telehealth service for eligible adults, with transparent all-inclusive first-month pricing: compounded semaglutide from $159 and tirzepatide from $279. Treatment is doctor-prescribed and supervised, with personalized care plans, multi-state clinical support, and at-home delivery from an FDA-registered compounding pharmacy. It carries verifiable LegitScript certification and 119 five-star reviews. Compounded medications are not FDA-approved; ongoing pricing may differ from the first-month rate and the pharmacy is unnamed.
Read our full LeanDose review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
LeanDose
What we like
- Transparent all-inclusive first-month pricing (compounded semaglutide from $159, tirzepatide from $279)
- Verifiable LegitScript certification (seal ID 49840868) and an FDA-registered compounding pharmacy
- Doctor-prescribed and supervised, with personalized care plans and multi-state clinical support
- Convenient at-home delivery; compounded semaglutide and tirzepatide options
- Honest, modest social proof — 119 five-star patient reviews
Watch-outs
- Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- Headline rates are first-month pricing; your ongoing monthly cost may be higher
- Available in multiple states but the full list is not published on the homepage
- The compounding pharmacy is FDA-registered but not named
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out LeanDose with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. LeanDose remains a solid alternative, especially if you're looking for Doctor-supervised compounded semaglutide or tirzepatide with transparent all-inclusive pricing.
Choose LeanDose if…
You want Doctor-supervised compounded semaglutide or tirzepatide with transparent all-inclusive pricing and a starting price around $159/mo.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online, ranked by our editorial score.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Telos Rx
Needle-free and microdosed compounded GLP-1 options with lab-monitored care
From $49/mo
Get started →Strut Health
Oral-lozenge compounded GLP-1 access
From $99/mo
Get started →Live Vital
Shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options
From $99/mo
Get started →LeanDose vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring LeanDose and Amazon One Medical head-to-heads in the same category.
- LeanDose vs CoreAge Rx
- LeanDose vs NovoCare Pharmacy
- LeanDose vs Vytora Health
- Amazon One Medical vs Enhance MD
- Amazon One Medical vs Noom Med
- Amazon One Medical vs Novi
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.