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InstaRX vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
InstaRX logo

InstaRX

6.8
★★★☆☆3.4/5

Best for: compounded GLP-1 plus peptides and sexual health on one account

Visit InstaRX
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

InstaRX and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

InstaRX

Get Started intake offerCompounded
$199/mo
semaglutide
Get Started intake offerCompounded
$199/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

InstaRX

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

InstaRX

6.8/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

5.8A
vs
B
8.3

Accessibility10%

8.5A
vs
B
8.5

Support10%

6.9A
vs
B
7.9

Features & Coverage

FeatureInstaRXNewSelf
Starting Price$199/mo$100/mo
Features8 features6 features
States Available5149
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About InstaRX

InstaRX is a multi-product compounded-medication telehealth platform offering GLP-1 injections (semaglutide and tirzepatide) alongside anti-aging peptides (NAD+, Sermorelin, B12/MIC) and sexual-health treatments on one account. Clinical care runs through an independent provider group, Dr Telx, with physicians licensed in all 50 states and DC. Public pricing is limited to a $199 “Get Started” intake offer.

Read our full InstaRX review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

InstaRX

What we like

  • Available in all 50 states plus DC
  • Manage GLP-1, anti-aging peptides, and sexual-health medications on one account
  • Offers both compounded semaglutide and compounded tirzepatide
  • Independent provider group (Dr Telx) named in the Terms of Service

Watch-outs

  • No per-dose or monthly pricing published — only a "$199 to get started" hook; you can't compare costs before intake
  • No LegitScript, HIPAA, or NABP accreditation shown on public pages
  • Compounding pharmacy not named — only "U.S. pharmacies"
  • Terms of Service reads like generic boilerplate, including copy-paste language about women's health issues — suggests low template hygiene
  • Delaware governing law for disputes despite a California corporate address
  • Corporate address is a strip-mall suite — suggests a pure-virtual operation

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out InstaRX with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. InstaRX remains a solid alternative, especially if you're looking for compounded GLP-1 plus peptides and sexual health on one account.

Choose InstaRX if…

You want compounded GLP-1 plus peptides and sexual health on one account and a starting price around $199/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.7

TrimRx

Best overall value

7.6

Sprout Health

LegitScript-verified compounded GLP-1 via named pharmacies

7.9

Trimi Health

Budget-conscious shoppers

InstaRX vs NewSelf: FAQ

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