HumeCare+ vs PlexusDx
In our scoring, HumeCare+ edges ahead overall (7.2 vs 7.0 out of 10).
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Key differences
- Price
- HumeCare+ $199/mo no prepay listed; PlexusDx $129/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- HumeCare+ 46 states + DC; PlexusDx 50 states (only HumeCare+: District of Columbia · only PlexusDx: Alabama, Arkansas, Louisiana and 1 more)
- Included
- HumeCare+: medication, clinician visits; PlexusDx: medication, clinician visits
HumeCare+
Affiliate partnerBest for GLP-1 weight loss with real-time body-composition tracking to protect muscle
semaglutide
$199
Our score 7.2/10
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
HumeCare+
PlexusDx
Price
Semaglutide / month
$199/mo
$129/mo
microdose plan
Semaglutide / year (modeled)
$2,388
$1,548
Tirzepatide / month
$299/mo
$249/mo
starting dose
Tirzepatide / year (modeled)
$3,588
$2,988
Oral semaglutide / month
$199/mo
Not listed
Coverage
State availability
46 states + DC
50 states
Oral option listed
Yes
Not listed
Included in the price
Medication, clinician visits
Medication, clinician visits
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Cancel anytime
Yes
Not disclosed
Minimum commitment
None
Not disclosed
Refunds
Terms: if the physician finds you ineligible the plan is refunded automatically and the Hume Pod must be returned. Otherwise there are no pro-rated refunds, and cancellation must be at least 48 hours before the renewal date. A clinical consultation fee assessed at enrollment and at each refill is carved out as non-refundable; its amount is not published.
Not disclosed
Early-cancellation fee
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only HumeCare+ (DC)
- District of Columbia
Only PlexusDx (4 states)
- Alabama
- Arkansas
- Louisiana
- Mississippi
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose HumeCare+ if…
- Lists oral compounded semaglutide, which PlexusDx doesn't price
- Serves District of Columbia, where PlexusDx doesn't
- Pairs compounded semaglutide with continuous body-composition tracking (lose fat, preserve muscle)
What to weigh up
- Not available in 4 states that PlexusDx serves
- No price appears on the marketing site; you must finish the intake quiz and give your name before one is quoted
Choose PlexusDx if…
- Serves 4 states that HumeCare+ doesn't
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
What to weigh up
- Not available in District of Columbia
- Compounded medications only; no FDA-approved brand options
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
HumeCare+
7.2/10
PlexusDx
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Luvo Health
Compounded and brand GLP-1s, oral tablets and microdosing on one public price list
Read full review →From $209/4 wks (billed per 4 weeks)
Get started →From $99/mo (“starting at” price)
Get started →Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →HumeCare+ vs PlexusDx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to HumeCare+ and PlexusDx.
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