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Hello Alpha vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Hello Alpha logo

Hello Alpha

7.2
★★★3.6/5

Best for: Brand-name GLP-1s and oral Foundayo, with insurance support

Visit Hello Alpha
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Hello Alpha and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Hello Alpha starts lower at $79/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Hello Alpha

Alpha Plus+ membership, monthly (medication billed separately)Brand-name
$79/mo
semaglutide

$79/month Alpha Plus+ is the weight-loss membership and includes "4 online visits per month"; a $29/month tier includes 2 visits. Medication is billed through insurance or LillyDirect, not the membership.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Hello Alpha

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Hello Alpha

7.2/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.9A
vs
B
7.9

Features & Coverage

FeatureHello AlphaNewSelf
Starting Price$79/mo$100/mo
Features8 features6 features
States AvailableNot disclosed49
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNone1 warning

About Hello Alpha

Hello Alpha (formerly Alpha Medical) is a US telehealth platform offering a full weight-loss lineup: branded GLP-1s including Wegovy, Ozempic, Rybelsus, Zepbound and Mounjaro, plus the oral GLP-1 Foundayo and other oral weight-loss medications. It works with insurance and provides ongoing clinician care through an online membership. Specific cash pricing and the full state list are not enumerated on the public site.

Read our full Hello Alpha review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Hello Alpha

What we like

  • Full branded GLP-1 lineup: Wegovy, Ozempic, Rybelsus, Zepbound, Mounjaro
  • Offers the oral GLP-1 Foundayo plus oral weight-loss medications
  • Works with insurance
  • Ongoing clinician care via online membership

Watch-outs

  • Cash pricing is not published on the public site
  • Full state list is not enumerated
  • Insurance coverage of the medication still depends on your plan

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Hello Alpha with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Hello Alpha remains a solid alternative, especially if you're looking for Brand-name GLP-1s and oral Foundayo, with insurance support.

Choose Hello Alpha if…

You want Brand-name GLP-1s and oral Foundayo, with insurance support and a starting price around $79/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

7.9

Trimi Health

Budget-conscious shoppers

8.0

ShedRx

Mainstream telehealth GLP-1 access

Hello Alpha vs NewSelf: FAQ

Hello Alpha is cheaper. Its lowest ongoing monthly cash price is $79/mo, compared with $100/mo for NewSelf. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 7.2/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, Hello Alpha is a better fit if you want Brand-name GLP-1s and oral Foundayo, with insurance support.
NewSelf lists availability in 49 states, while Hello Alpha's state list is not publicly listed.
Neither Hello Alpha nor NewSelf is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Hello Alpha is cheaper at $79/mo versus $100/mo at NewSelf.

Key terms, explained

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Continue exploring Hello Alpha and NewSelf head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.