Genesis Lifestyle Medicine vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Genesis Lifestyle Medicine
Best for: hybrid med-spa GLP-1 with 18 clinics and brand-name access
Visit Genesis Lifestyle Medicine →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Genesis Lifestyle Medicine and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Genesis Lifestyle Medicine
Pricing not publicly listed.
NewSelf
All dosages same price
All dosages same price
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What’s included
Genesis Lifestyle Medicine
Inclusions not disclosed.
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Genesis Lifestyle Medicine
6.6/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Genesis Lifestyle Medicine | NewSelf |
|---|---|---|
| Starting Price | — | $100/mo |
| Features | ✓8 features | 6 features |
| States Available | 8 | ✓49 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Genesis Lifestyle Medicine
Genesis Lifestyle Medicine is a hybrid in-office and telehealth medical spa with 18 clinic locations across 8 states, offering brick-and-mortar accountability uncommon among DTC GLP-1 providers. It spans weight loss, hormone therapy, aesthetics, and hair restoration. For weight loss it offers both compounded semaglutide and tirzepatide and brand-name Wegovy and Zepbound, so patients who prefer FDA-approved options needn't switch platforms.
Read our full Genesis Lifestyle Medicine review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Genesis Lifestyle Medicine
What we like
- 18 physical clinics allow in-person consults and injections across 8 states
- Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
- Med spa model lets patients combine weight loss, hormone therapy, and aesthetics
- Established brand with an 18-location footprint and patient testimonials
- Telehealth available for remote patients in served states
- LegitScript verified
Watch-outs
- Pricing not disclosed publicly — gated behind the consultation flow
- Specific 503A/503B pharmacy partner not named, and the designation not specified
- No FDA compounded-medication disclaimer visible on the homepage
- Named medical director not formally disclosed (only a 'Dr. Spinoso' testimonial)
- Corporate legal entity and governing law not disclosed
- Only 8 states served — much narrower than national competitors
- Telehealth runs on a separate domain, fragmenting the brand trail
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Genesis Lifestyle Medicine with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Genesis Lifestyle Medicine remains a solid alternative, especially if you're looking for hybrid med-spa GLP-1 with 18 clinics and brand-name access.
Choose Genesis Lifestyle Medicine if…
You want hybrid med-spa GLP-1 with 18 clinics and brand-name access.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →ShedRx
Mainstream telehealth GLP-1 access
From $149/mo
Get started →Genesis Lifestyle Medicine vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.