Effecty vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Effecty
Best for: nationwide compounded semaglutide with brand-name fallback
Visit Effecty →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Effecty and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $160/mo, and NewSelf edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Effecty
$60 first month, then $160/mo on the 12-month plan.
$105 first month, then $205/mo.
NEW tirzepatide-class dual-agonist line. $140 first month, then $240/mo on the 12-month plan.
$205 first month, then $305/mo.
NewSelf
All dosages same price
All dosages same price
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What’s included
Effecty
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Effecty
7.5/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Effecty | NewSelf |
|---|---|---|
| Starting Price | $160/mo | ✓$100/mo |
| Features | ✓7 features | 6 features |
| States Available | ✓50 | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Effecty
Effecty offers compounded GLP-1 injections ($160–$205/mo) plus brand-name Ozempic, Wegovy, Zepbound, and Mounjaro. LegitScript certified. Ships to all states nationwide. No membership fees.
Read our full Effecty review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Effecty
What we like
- Both compounded and brand-name GLP-1 options (Ozempic, Wegovy, Zepbound, Mounjaro)
- LegitScript certified
- Ships to all states nationwide
- No membership fees — transparent pricing
- Compounded semaglutide from $160/mo on annual plan
- Compounded GLP-1+GIP (tirzepatide-class dual agonist) now available from $240/mo ($140 first month)
Watch-outs
- Brand-name options at full retail price ($1,300–$1,600/mo)
- Also offers longevity and women's HRT (broader platform)
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Effecty with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Effecty remains a solid alternative, especially if you're looking for nationwide compounded semaglutide with brand-name fallback.
Choose Effecty if…
You want nationwide compounded semaglutide with brand-name fallback and a starting price around $160/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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RxSpan MD
Shoppers wanting physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From $179/mo
Get started →Strut Health
Oral-lozenge compounded GLP-1 access
From $99/mo
Get started →Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →Effecty vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.