EdgeRx vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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EdgeRx
Best for: men wanting a physician-led peptide clinic, though its GLP-1 line isn't orderable yet
Visit EdgeRx →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →EdgeRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $229/mo, and NewSelf edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
EdgeRx
Formulated with glycine + B12; compounded by Strive Pharmacy (503A). Protocol page states 'The Semaglutide protocol is not currently available for purchase.'
Formulated with glycine + B12; compounded by Strive Pharmacy (503A). Protocol page states 'The Tirzepatide protocol is not currently available for purchase.'
NewSelf
All dosages same price
All dosages same price
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What’s included
EdgeRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
EdgeRx
6.8/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | EdgeRx | NewSelf |
|---|---|---|
| Starting Price | $229/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | 46 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About EdgeRx
EdgeRx is a men's peptide and longevity telehealth platform from EdgeRx Health, LLC. Semaglutide and Tirzepatide injections, each formulated with muscle-preserving glycine and B12, sit alongside four other outcome categories (recovery, cognition, hair, sexual health) and are compounded by a single named 503A pharmacy, Strive Pharmacy. Protocols are cash-pay with HSA/FSA accepted through Truemed, and physician review is included in the price. As of this review, both GLP-1 injections are priced and described on the site but are waitlist-only — checkout is not yet live for any protocol.
Read our full EdgeRx review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
EdgeRx
What we like
- Board-certified physicians prescribe every protocol, not a nurse-practitioner questionnaire
- Single named 503A pharmacy partner, Strive Pharmacy, compounding since 2018
- LegitScript seal independently verified live (returns 200 OK), a real certification
- GLP-1 doses formulated with glycine and B12 for muscle preservation and reduced nausea
- Free shipping on every order, including temperature-sensitive injectables
- HSA/FSA reimbursable through Truemed; transparent cash-pay pricing, no insurance games
- Cancel or pause anytime with no cancellation fee and no minimum commitment
- Refunded in full if a physician doesn't approve your protocol
Watch-outs
- Semaglutide and Tirzepatide are not currently available for purchase — waitlist only
- Checkout is 'coming soon' sitewide; no protocol on the entire site can currently be purchased
- You're charged before the medical assessment and physician review even happen
- MICC add-on price is inconsistent on EdgeRx's own site: $49/mo on protocol pages vs. $79/mo in the category FAQ
- Not available in Arkansas, Indiana, Minnesota, or South Carolina
- No published support phone number or stated customer-service hours — email only
- Binding arbitration and class-action waiver in the Terms of Service
- Men's-only branding and formulations — not an option for women
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out EdgeRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. EdgeRx remains a solid alternative, especially if you're looking for men wanting a physician-led peptide clinic, though its GLP-1 line isn't orderable yet.
Choose EdgeRx if…
You want men wanting a physician-led peptide clinic, though its GLP-1 line isn't orderable yet and a starting price around $229/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
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Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
From $199/mo
Get started →GobyMeds
Budget-conscious shoppers
From $93/mo
Get started →EdgeRx vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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