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Edessa vs Vytora Health

In our scoring, Vytora Health edges ahead overall (8.4 vs 7.3 out of 10), and both cost the same for compounded semaglutide.

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Both $179/mo for compounded semaglutide (standing prices, no prepay listed)
Coverage
Both serve the same 50 states + DC
Included
Edessa: medication, clinician visits, shipping; Vytora Health: medication, clinician visits, shipping

How we compare providers

Edessa logo

Edessa

Best for cheap month-to-month compounded GLP-1 with tirzepatide and an oral tablet option

semaglutide

$179/mo

Our score 7.3/10

Vytora Health logo

Vytora Health

Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states

semaglutide

$179/mo

Our score 8.4/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Edessa

Vytora Health

Price

Semaglutide / month

$179/mo

$179/mo

Semaglutide / year (modeled)

$2,148

$2,148

Tirzepatide / month

Better on this row: $239/mo

$249/mo

Tirzepatide / year (modeled)

Better on this row: $2,868

$2,988

Oral semaglutide / month

$229/mo

Not listed

Brand Zepbound / Mounjaro / month

Not listed

$1,399/mo

Coverage

State availability

50 states + DC

50 states + DC

Oral option listed

Yes

Not listed

Brand-name access listed

Not listed

Zepbound / Mounjaro

Included in the price

Medication, clinician visits, shipping

Medication, clinician visits, shipping

FSA/HSA accepted

Yes

Not listed

Terms & safety

Price shown

Before intake

Before intake

Cancel anytime

Not disclosed

Yes

Minimum commitment

1-, 3- or 6-month plans; the 3- and 6-month rates are per-month figures on a prepaid term

None on monthly plans; 3-month plans are billed every 3 months

Refunds

'You will be eligible for a refund of your payment (minus dr. consult fees of 25%) if you can demonstrate that you have not lost weight after following our weight loss program for a minimum of 5 months.' The same section says 'We cannot accept returns of prescription products for reuse or resale, and all sales are final' and that consult fees are not refundable

'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'

FDA warning letters

None on record

None on record

Provider facts checked

September 2026

October 2026

Every dose and plan: Edessa · Vytora Health

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Edessa logo

Choose Edessa if…

  • Lists oral compounded semaglutide, which Vytora Health doesn't price
  • Accepts FSA/HSA cards
  • Tirzepatide and a daily dissolvable tablet sit alongside the standard weekly injection

What to weigh up

  • '$135' is the six-month prepay rate; month-to-month is $179, yet the FAQ still calls $135 a first-month price 'with no contract'
  • The 'no questions asked' guarantee is not the policy: the Terms need proof of no weight loss after five months, minus 25% consult fees
Vytora Health logo

Choose Vytora Health if…

  • Lists brand-name Zepbound / Mounjaro, which Edessa doesn't price
  • Both compounded and brand-name options on one platform
  • Displays a LegitScript seal and says it is HIPAA compliant

What to weigh up

  • Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
  • Compounded tirzepatide at $249/mo month-to-month is mid-market

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Edessa

7.3/10

Overall

Vytora Health

8.4/10

Value25%

8.0A
vs
B
8.0

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
9.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

6.5A
vs
B
8.4

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No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle

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Ivim Health

Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership

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6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

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Edessa vs Vytora Health: FAQ

For compounded semaglutide, Edessa and Vytora Health cost the same over a year, so price alone won't separate them — compare what each plan includes instead.
Vytora Health scores higher overall at 8.4/10 versus 7.3/10, and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. That said, Edessa is a better fit if you want cheap month-to-month compounded GLP-1 with tirzepatide and an oral tablet option.
Neither Edessa nor Vytora Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
Edessa: $179, about $2,148 a year. Vytora Health: $179, about $2,148 a year. They cost the same over a year.
Both publish the same list (50 states + DC), so where you live won't decide between them.
Edessa: cancel anytime — not disclosed; minimum commitment — 1-, 3- or 6-month plans; the 3- and 6-month rates are per-month figures on a prepaid term; early-cancellation fee — not disclosed. Vytora Health: cancel anytime — yes; minimum commitment — None on monthly plans; 3-month plans are billed every 3 months; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Edessa and Vytora Health head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.