Direct Meds vs Willow
In our scoring, Willow edges ahead overall (7.2 vs 6.4 out of 10), and Direct Meds costs less for compounded semaglutide (about $24 a year less).
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Key differences
- Price
- Direct Meds $297/mo vs Willow $299/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $24 a year less with Direct Meds)
- Coverage
- Willow 36 states (Direct Meds doesn't publish a state list)
- Included
- Direct Meds: medication, clinician visits, shipping; Willow: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: Direct Meds 1, Willow none
Direct Meds
Affiliate partnerAbout $24 a year less for compounded semaglutide
semaglutide
$297
Our score 6.4/10
Willow
Affiliate partnerBest for needle-free compounded semaglutide or tirzepatide tablets
semaglutide
$299
Our score 7.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Direct Meds
Willow
Price
Semaglutide / month
Better on this row: $297/mo
$299/mo
Semaglutide / year (modeled)
Better on this row: $3,564
$3,588
Tirzepatide / month
$399/mo
$399/mo
Tirzepatide / year (modeled)
$4,788
$4,788
Oral semaglutide / month
Better on this row: $249/mo
$299/mo
Oral semaglutide / year (modeled)
Better on this row: $2,988
$3,588
Oral tirzepatide / month
Better on this row: $299/mo
$399/mo
Oral tirzepatide / year (modeled)
Better on this row: $3,588
$4,788
Coverage
State availability
List not published
36 states
Oral option listed
Yes
Yes
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
No
Better on this row: Yes
Minimum commitment
3-month prepay
Monthly auto-renewing plan; no minimum term stated. 'Your program renews automatically so you never miss a dose.'
Refunds
Not disclosed
'If you cancel before your prescription is sent to the pharmacy, you'll receive a full refund within 5-10 business days.' Terms: 'charges are non-refundable once incurred' and prescription products 'are not returnable'.
Early-cancellation fee
Yes
Not disclosed
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
August 2026
October 2026
Every dose and plan: Direct Meds · Willow
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Direct Meds if…
- About $24 a year less than Willow for compounded semaglutide at standing prices
- All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
- LegitScript Certified
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
Choose Willow if…
- Publishes its full state list (36 states)
- Cancel anytime
- No FDA warning letters on record (Direct Meds has 1)
What to weigh up
- About $24 a year more than Direct Meds for compounded semaglutide
- Pricier than many compounded programs: $299/mo for semaglutide and $399/mo for tirzepatide
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Direct Meds
6.4/10
Willow
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →Direct Meds vs Willow: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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