CoreAge Rx vs Signos
An in-depth comparison of two leading GLP-1 Providers
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Signos
Best for: Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app
Visit Signos →CoreAge Rx and Signos are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $149/mo versus $199/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
CoreAge Rx
Signos
Signos+ GLP-1 bundle (tirzepatide OR semaglutide) from $199/mo; includes CGM system
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What’s included
CoreAge Rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Signos
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
CoreAge Rx
8.3/10
Signos
7.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | CoreAge Rx | Signos |
|---|---|---|
| Starting Price | ✓$149/mo | $199/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About CoreAge Rx
CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.
Read our full CoreAge Rx review →About Signos
Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with real-time glucose data and coaching so users understand and sustain their weight loss. The program starts at $199/mo on a 6-month plan, includes free shipping, and is HSA/FSA eligible. It is pitched as the same price as medication alone, with the CGM added.
Read our full Signos review →Pros & Cons
CoreAge Rx
What we like
- LegitScript certified — rigorous pharmacy standards
- Free 2-day shipping nationwide
- Both semaglutide and tirzepatide available
- Lowest per-month pricing in the compounded segment
- 24/7 support team
- All 50 states covered
Watch-outs
- Compounded only — no brand-name Ozempic or Wegovy
- Newer brand with fewer independent reviews than legacy players
Signos
What we like
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Watch-outs
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Our Verdict
CoreAge Rx edges out Signos with a higher overall score of 8.3/10 and is particularly strong for best overall value. Signos remains a solid alternative, especially if you're looking for Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
Choose CoreAge Rx if…
You want best overall value and a starting price around $149/mo.
Choose Signos if…
You want Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app and a starting price around $199/mo.
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Compounded semaglutide and tirzepatide at a flat monthly price
From $119/mo
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Compounded or brand GLP-1 bundled with TRT and peptides for men
From $100/mo
Get started →CoreAge Rx vs Signos: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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