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CoreAge Rx vs Onyx Weight Loss

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
Onyx Weight Loss logo

Onyx Weight Loss

6.2
★★★☆☆3.1/5

Best for: NP-led GLP-1 telehealth in 8 states; sema $228/mo or tirz $280/mo, all-in

Visit Onyx Weight Loss

CoreAge Rx and Onyx Weight Loss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $99/mo, and CoreAge Rx edges ahead overall (8.3 vs 6.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Onyx Weight Loss

Starting doseCompounded
$228/mo
semaglutide

Verbatim: 'Starting at $228/month' (GLP-1 Agonist plan). Includes medication and supplies shipped to home. Entry tier only; higher-dose pricing not disclosed.

Starting doseCompounded
$280/mo
tirzepatide

Verbatim: 'Starting at $280/month' (GLP-1/GIP Agonist plan). Includes medication and supplies. Entry tier only; specific drug name inferred from GLP-1/GIP dual agonist designation.

MicrodoseCompounded
$99/mo
semaglutide

Verbatim: '$99/MONTH' (GLP-1 Microdosing plan). Low-dose gradual-start option.

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Onyx Weight Loss

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

Onyx Weight Loss

6.2/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
6.5

User Experience15%

8.5A
vs
B
5.5

Trust & Safety15%

7.8A
vs
B
5.8

Accessibility10%

8.0A
vs
B
4.0

Support10%

8.4A
vs
B
7.4

Features & Coverage

FeatureCoreAge RxOnyx Weight Loss
Starting Price$99/mo$99/mo
Features6 features8 features
States Available508
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About Onyx Weight Loss

Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states. Founded by Tasha Vangile FNP-C and Madalyn Vangile RN, plans start at $228/month for GLP-1 (semaglutide-type) and $280/month for GLP-1/GIP (tirzepatide-type), with medication and supplies shipped home via Strive Pharmacy partner. A $99/month GLP-1 microdosing option is also available for a gradual-titration start.

Read our full Onyx Weight Loss review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Onyx Weight Loss

What we like

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Watch-outs

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Onyx Weight Loss with a higher overall score of 8.3/10 and is particularly strong for best overall value. Onyx Weight Loss remains a solid alternative, especially if you're looking for NP-led GLP-1 telehealth in 8 states; sema $228/mo or tirz $280/mo, all-in.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

Choose Onyx Weight Loss if…

You want NP-led GLP-1 telehealth in 8 states; sema $228/mo or tirz $280/mo, all-in and a starting price around $99/mo.

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8.0

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6.9

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CoreAge Rx vs Onyx Weight Loss: FAQ

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