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CoreAge Rx vs Enhance MD

An in-depth comparison of two leading GLP-1 Providers

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CoreAge Rx logo

CoreAge Rx

9.0
★★★★4.5

Best for: best overall value

Visit CoreAge Rx
VS
Enhance MD logo

Enhance MD

8.6
★★★★4.3

Best for: lab-monitored compounded GLP-1 with mandatory video visit

Visit Enhance MD

CoreAge Rx and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $149/mo versus $212/mo, and Enhance MD is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

0.25mgCompounded
$149/mo
semaglutide
0.5mgCompounded
$199/mo
semaglutide
1mgCompounded
$249/mo
semaglutide
1.7mgCompounded
$299/mo
semaglutide
2.5mgCompounded
$349/mo
tirzepatide

Enhance MD

GLP-1 CoreCompounded
$212$49/mo
Save 77% right now
semaglutide
GLP-1 AdvancedCompounded
$280$99/mo
Save 65% right now
tirzepatide
GLP-1 Elite (sema + tirz)Compounded
$322$189/mo
Save 41% right now
tirzepatide

What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Enhance MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Included

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

9.0/10

Overall

Enhance MD

8.6/10

Value25%

9.5A
vs
B
8.5

Effectiveness25%

8.5A
vs
B
8.5

User Experience15%

9.0A
vs
B
8.5

Trust & Safety15%

9.0A
vs
B
8.5

Accessibility10%

9.0A
vs
B
9.0

Support10%

8.5A
vs
B
9.0

Features & Coverage

FeatureCoreAge RxEnhance MD
Starting Price$149/mo$212/mo
Features6 features6 features
States Available5039
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About Enhance MD

Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).

Read our full Enhance MD review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Enhance MD

What we like

  • Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
  • Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
  • Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
  • Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
  • Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
  • Unlimited clinician messaging and dose-adjustment support included

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
  • Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
  • No insurance accepted — cash pay, HSA/FSA eligible
  • Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost

Our Verdict

Winner: Enhance MD

Enhance MD is our recommended choice here, particularly for lab-monitored compounded GLP-1 with mandatory video visit. CoreAge Rx is a solid alternative, especially if you want best overall value — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose CoreAge Rx if…

You want best overall value and a starting price around $149/mo.

Choose Enhance MD if…

You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.

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Lab-monitored compounded GLP-1 with mandatory video visit

CoreAge Rx vs Enhance MD: FAQ

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