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Collective vs PlexusDx

In our scoring, Collective edges ahead overall (8.3 vs 7.0 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Collective $59/mo plus a separate membership; PlexusDx $129/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
Coverage
Collective 44 states; PlexusDx 50 states (only PlexusDx: Alabama, California, Louisiana and 3 more)
Included
Collective: medication, clinician visits, shipping; PlexusDx: medication, clinician visits

How we compare providers

Collective logo

Collective

Affiliate partner

Best for the lowest flat medication price if you can absorb an annual membership fee

semaglutide

$59/mo

+ separate membership

Our score 8.3/10

PlexusDx logo

PlexusDx

Affiliate partner

Best for nationwide compounded GLP-1 with optional genetic-test personalization

semaglutide

$129/mo

microdose plan

Our score 7.0/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Collective

PlexusDx

Price

Semaglutide / month

$59/mo

+ separate membership

$129/mo

microdose plan

Semaglutide / year (modeled)

$708

excludes the membership

$1,548

Tirzepatide / month

$69/mo

+ separate membership

$249/mo

starting dose

Tirzepatide / year (modeled)

$828

excludes the membership

$2,988

Separate membership required

Yes — not in the listed price

Not stated

Coverage

State availability

44 states

50 states

Included in the price

Medication, clinician visits, shipping

Medication, clinician visits

Terms & safety

Price shown

Before intake

Before intake

Cancel anytime

Yes

Not disclosed

Minimum commitment

Medication is month-to-month; the membership is billed annually

Not disclosed

Refunds

'All membership fees are non-refundable, and partial-period refunds are not provided.'

Not disclosed

Early-cancellation fee

None

Not disclosed

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Show where they differ by state

Only PlexusDx (6 states)

  • Alabama
  • California
  • Louisiana
  • Massachusetts
  • Mississippi
  • Washington

Every dose and plan: Collective · PlexusDx

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Collective logo

Choose Collective if…

  • Flat pricing at every dose, so titrating up does not raise the bill
  • Unlimited doctor messaging, quarterly check-ins and registered-dietitian access are included rather than upsold
  • An optional twice-a-week dosing schedule and anti-nausea prescriptions when needed, aimed at the side effects that make people quit

What to weigh up

  • Listed compounded semaglutide price excludes a required membership
  • Not available in 6 states that PlexusDx serves
PlexusDx logo

Choose PlexusDx if…

  • Serves 6 states that Collective doesn't
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform

What to weigh up

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Collective

8.3/10

Overall

PlexusDx

7.0/10

Value25%

9.4A
vs
B
7.0

Effectiveness25%

8.2A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

7.2A
vs
B
6.8

Accessibility10%

7.4A
vs
B
7.5

Support10%

8.4A
vs
B
6.5

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6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

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From $249/mo

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7.7

Ro

FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help

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From $149/mo (+ required membership)

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8.0

ShedRx

Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans

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From $299/mo (after intro offer)

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Collective vs PlexusDx: FAQ

Collective scores higher overall at 8.3/10 versus 7.0/10, and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. That said, PlexusDx is a better fit if you want nationwide compounded GLP-1 with optional genetic-test personalization.
Both Collective and PlexusDx are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Collective: $59, medication only (a separate membership is required), about $708 a year. PlexusDx: $129, about $1,548 a year. Not like-for-like: one figure excludes a required membership.
Both serve 44 states. Only PlexusDx serves Alabama, California, Louisiana, Massachusetts, Mississippi and Washington.
Collective: cancel anytime — yes; minimum commitment — Medication is month-to-month; the membership is billed annually; early-cancellation fee — none. PlexusDx doesn't state its cancellation terms. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Collective and PlexusDx head-to-heads in the same category.

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