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Collective vs Fifty 410

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Collective logo

Collective

8.3
★★★★4.2/5

Best for: the lowest flat medication price if you can absorb an annual membership fee

Visit Collective
VS
Fifty 410 logo

Fifty 410

7.0
★★★3.5/5

Best for: transparent no-membership compounded GLP-1 pricing

Visit Fifty 410

Collective and Fifty 410 are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Collective starts lower at $59/mo versus $99/mo, and Collective edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Collective

Any dose (flat price)Compounded
$59/mo
semaglutide

Verbatim: 'Compounded Semaglutide: $59/month. Same price, every dose. Cancel anytime.' ⛔ EXCLUDES the required membership — the site states 'What does it cost? $59/month + $199 annual membership.' First-year total is $907 ($75.58/mo equivalent).

Any dose (flat price)Compounded
$69/mo
tirzepatide

Verbatim: 'Compounded Tirzepatide: $69/month. Same price, any dose.' ⛔ EXCLUDES the required membership — 'The cost is $69/month + $199 annual membership.' First-year total is $1,027 ($85.58/mo equivalent).

Required annual membership (subscription, medication billed separately)membership subscription
$199/mo

Verbatim: 'Requires Collective membership: 21 day free trial, then a low annual $199 membership fee. No recurring monthly membership charges.' Charged yearly, not monthly. Terms of Use: 'all membership fees are non-refundable, and partial-period refunds are not provided.'

Fifty 410

Flat-rate (all doses)Compounded
$99/mo
semaglutide
StarterCompounded
$133/mo
tirzepatide

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What’s included

Collective

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Fifty 410

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Collective

8.3/10

Overall

Fifty 410

7.0/10

Value25%

9.4A
vs
B
7.0

Effectiveness25%

8.2A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

7.2A
vs
B
6.8

Accessibility10%

7.4A
vs
B
7.0

Support10%

8.4A
vs
B
7.5

Features & Coverage

FeatureCollectiveFifty 410
Starting Price$59/mo$99/mo
Features3 features8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNone1 warning

About Collective

Collective (collective.org) is a membership-based telehealth platform from the founder of Thrive Market, selling compounded semaglutide and tirzepatide at a flat price on every dose. Medication is billed separately from a required annual membership, and the program bundles unlimited clinician messaging, dietitian access and express cold shipping.

Read our full Collective review →

About Fifty 410

Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B pharmacies. It uses a no-membership, pay-as-you-go model with transparent public pricing: semaglutide from 99 dollars per month and tirzepatide starter from 133 dollars per month, plus a high-dose tier. Provider reviews finish in 24 to 48 hours and free shipping arrives in one to two days. Cash-pay only; no direct insurance billing, but accepts FSA/HSA, Afterpay, and Affirm.

Read our full Fifty 410 review →

Pros & Cons

Collective

What we like

  • The lowest published compounded GLP-1 medication prices we track — $59/month semaglutide and $69/month tirzepatide
  • Flat pricing at every dose, so titrating up does not raise the bill
  • Unlimited clinician messaging and registered-dietitian access are included rather than upsold
  • 21-day free trial on the membership before the annual fee is charged

Watch-outs

  • The advertised $59 and $69 exclude a mandatory $199 annual membership — the real first-year cost is $907 and $1,027
  • Membership fees are non-refundable and no partial-period refunds are given
  • Compounding pharmacies are described only as 'independent, third-party licensed pharmacies' and are never named
  • State availability is not published on the marketing site

Fifty 410

What we like

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping
  • Accepts FSA/HSA plus Afterpay and Affirm

Watch-outs

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options

Our Verdict

Winner: Collective

Collective edges out Fifty 410 with a higher overall score of 8.3/10 and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. Fifty 410 remains a solid alternative, especially if you're looking for transparent no-membership compounded GLP-1 pricing.

Choose Collective if…

You want the lowest flat medication price if you can absorb an annual membership fee and a starting price around $59/mo.

Choose Fifty 410 if…

You want transparent no-membership compounded GLP-1 pricing and a starting price around $99/mo.

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Collective vs Fifty 410: FAQ

Collective is cheaper. Its lowest ongoing monthly cash price is $59/mo, compared with $99/mo for Fifty 410. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Collective scores higher overall at 8.3/10 versus 7.0/10, and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. That said, Fifty 410 is a better fit if you want transparent no-membership compounded GLP-1 pricing.
Neither Collective nor Fifty 410 publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither Collective nor Fifty 410 is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Collective is cheaper at $59/mo versus $99/mo at Fifty 410.

Key terms, explained

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Continue exploring Collective and Fifty 410 head-to-heads in the same category.

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