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Collective vs Enhance MD

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Collective logo

Collective

8.3
★★★★4.2/5

Best for: the lowest flat medication price if you can absorb an annual membership fee

Visit Collective
VS
Enhance MD logo

Enhance MD

8.2
★★★★4.1/5

Best for: lab-monitored compounded GLP-1 with mandatory video visit

Visit Enhance MD

Collective and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Collective starts lower at $59/mo versus $169/mo, and Enhance MD is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Collective

Any dose (flat price)Compounded
$59/mo
semaglutide

Verbatim: 'Compounded Semaglutide: $59/month. Same price, every dose. Cancel anytime.' ⛔ EXCLUDES the required membership — the site states 'What does it cost? $59/month + $199 annual membership.' First-year total is $907 ($75.58/mo equivalent).

Any dose (flat price)Compounded
$69/mo
tirzepatide

Verbatim: 'Compounded Tirzepatide: $69/month. Same price, any dose.' ⛔ EXCLUDES the required membership — 'The cost is $69/month + $199 annual membership.' First-year total is $1,027 ($85.58/mo equivalent).

Required annual membership (subscription, medication billed separately)membership subscription
$199/mo

Verbatim: 'Requires Collective membership: 21 day free trial, then a low annual $199 membership fee. No recurring monthly membership charges.' Charged yearly, not monthly. Terms of Use: 'all membership fees are non-refundable, and partial-period refunds are not provided.'

Enhance MD

GLP-1 CoreCompounded
$212$112/mo
Save 47% right now
semaglutide

$212/mo is the 12-month-plan rate (billed every 48 weeks). 6-mo $224/mo, 3-mo $237/mo, 1-mo $249/mo. First month $112 = $100 off first order on 3+ month plans (code SUMMER100); $50 off 1-month (SUMMER50). Flat price at all doses; labs, consult, 2-day shipping included.

GLP-1 AdvancedCompounded
$280$180/mo
Save 36% right now
tirzepatide

$280/mo = 12-month-plan rate. 6-mo $296/mo, 3-mo $313/mo, 1-mo $329/mo. First month $180 via $100-off first order (SUMMER100). Flat all-dose pricing.

GLP-1 Elite (sema + tirz)Compounded
$322$222/mo
Save 31% right now
tirzepatide

Combined semaglutide + tirzepatide. $322/mo = 12-month-plan rate. 6-mo $341/mo, 3-mo $360/mo, 1-mo $379/mo. First month $222 via SUMMER100.

Microdosing Tirzepatide (NEW product)Compounded
$169/mo
tirzepatide

Low-dose tier, and it is prepay-only: 12-month $169/mo, 6-month $179/mo, 3-month $189/mo. No one-month option is offered for microdosing at all.

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What’s included

Collective

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Enhance MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Included

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Collective

8.3/10

Overall

Enhance MD

8.2/10

Value25%

9.4A
vs
B
7.0

Effectiveness25%

8.2A
vs
B
9.0

User Experience15%

8.0A
vs
B
8.5

Trust & Safety15%

7.2A
vs
B
8.0

Accessibility10%

7.4A
vs
B
8.5

Support10%

8.4A
vs
B
8.9

Features & Coverage

FeatureCollectiveEnhance MD
Starting Price$59/mo$169/mo
Features3 features6 features
States AvailableNot disclosed39
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Collective

Collective (collective.org) is a membership-based telehealth platform from the founder of Thrive Market, selling compounded semaglutide and tirzepatide at a flat price on every dose. Medication is billed separately from a required annual membership, and the program bundles unlimited clinician messaging, dietitian access and express cold shipping.

Read our full Collective review →

About Enhance MD

Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus $100-off-first-order intro pricing ($112 first month on Core with code SUMMER100).

Read our full Enhance MD review →

Pros & Cons

Collective

What we like

  • The lowest published compounded GLP-1 medication prices we track — $59/month semaglutide and $69/month tirzepatide
  • Flat pricing at every dose, so titrating up does not raise the bill
  • Unlimited clinician messaging and registered-dietitian access are included rather than upsold
  • 21-day free trial on the membership before the annual fee is charged

Watch-outs

  • The advertised $59 and $69 exclude a mandatory $199 annual membership — the real first-year cost is $907 and $1,027
  • Membership fees are non-refundable and no partial-period refunds are given
  • Compounding pharmacies are described only as 'independent, third-party licensed pharmacies' and are never named
  • State availability is not published on the marketing site

Enhance MD

What we like

  • Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
  • Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
  • Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
  • Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
  • Intro pricing via $100 off your first order (code SUMMER100): $112 Core, $180 Advanced, $222 Elite first month
  • Unlimited clinician messaging and dose-adjustment support included

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
  • Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
  • No insurance accepted — cash pay, HSA/FSA eligible
  • Intro discount applies only to the first order — ongoing rates are $212–$322/mo on 12-month plans, or $249–$379/mo month-to-month

Our Verdict

Winner: Enhance MD

Enhance MD is our recommended choice here, particularly for lab-monitored compounded GLP-1 with mandatory video visit. Collective is a solid alternative, especially if you want the lowest flat medication price if you can absorb an annual membership fee — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose Collective if…

You want the lowest flat medication price if you can absorb an annual membership fee and a starting price around $59/mo.

Choose Enhance MD if…

You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $169/mo.

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Collective vs Enhance MD: FAQ

Collective is cheaper. Its lowest ongoing monthly cash price is $59/mo, compared with $169/mo for Enhance MD. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
For most people we'd start with Enhance MD, especially if you want lab-monitored compounded GLP-1 with mandatory video visit. Collective is a strong alternative and may suit you better for the lowest flat medication price if you can absorb an annual membership fee — weigh the six-dimension breakdown above to decide which fits your priorities.
Enhance MD lists availability in 39 states, while Collective's state list is not publicly listed.
Enhance MD is an affiliate partner (we may earn a commission on sign-ups through our links); Collective is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, Collective is cheaper at $59/mo versus $112/mo at Enhance MD.

Key terms, explained

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Continue exploring Collective and Enhance MD head-to-heads in the same category.

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