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Blis MD vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Blis MD

7.0
★★★3.5/5

Best for: people who want transparent flat-price compounded semaglutide or tirzepatide with provider check-ins

Visit Blis MD
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Blis MD and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $139/mo, and NewSelf edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Blis MD

All doses (flat)Compounded
$139/mo
semaglutide

Flat monthly; includes medication and provider check-ins

All doses (flat)Compounded
$199/mo
tirzepatide

Flat monthly; includes bi-weekly check-ins

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Blis MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Blis MD

7.0/10

Overall

NewSelf

8.3/10

Value25%

7.6A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
8.3

Accessibility10%

6.0A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureBlis MDNewSelf
Starting Price$139/mo$100/mo
Features6 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Blis MD

Blis MD is a US telehealth offering personalized GLP-1 weight-loss treatment with compounded semaglutide and tirzepatide, prescribed after a free virtual consultation with a licensed provider. Pricing is transparent and flat: semaglutide is 139 dollars per month and tirzepatide is 199 dollars per month, each including a monthly medication supply, personalized dosing, and provider check-ins. Blis MD also markets other wellness peptides such as BPC-157, NAD plus, and Sermorelin. Compounded medications are not FDA-approved. Contact is by phone and email; specific states served are not published.

Read our full Blis MD review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Blis MD

What we like

  • Transparent flat monthly pricing published upfront (139 dollars semaglutide, 199 dollars tirzepatide)
  • Free initial virtual consultation with a licensed provider
  • Both semaglutide and tirzepatide offered with ongoing provider check-ins

Watch-outs

  • Compounding pharmacy is not named publicly
  • States served are not listed on the site
  • Thin public trust signals (no LegitScript seal or named medical director found)

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Blis MD with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Blis MD remains a solid alternative, especially if you're looking for people who want transparent flat-price compounded semaglutide or tirzepatide with provider check-ins.

Choose Blis MD if…

You want people who want transparent flat-price compounded semaglutide or tirzepatide with provider check-ins and a starting price around $139/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Blis MD vs NewSelf: FAQ

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