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AVARA Rx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
AVARA Rx logo

AVARA Rx

6.6
★★★☆☆3.3/5

Best for: 50-state compounded GLP-1 with named pharmacy and clinical network

Visit AVARA Rx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

AVARA Rx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $229/mo, and NewSelf edges ahead overall (8.3 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

AVARA Rx

Starting tiercompounded injection
$229/mo
semaglutide
Starting tiercompounded injection
$279/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

AVARA Rx

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

AVARA Rx

6.6/10

Overall

NewSelf

8.3/10

Value25%

6.0A
vs
B
9.0

Effectiveness25%

6.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

8.0A
vs
B
8.5

Support10%

6.4A
vs
B
7.9

Features & Coverage

FeatureAVARA RxNewSelf
Starting Price$229/mo$100/mo
Features8 features6 features
States Available5049
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About AVARA Rx

AVARA Rx is a nationwide DTC telehealth platform offering compounded semaglutide and tirzepatide plus brand-name Wegovy, Zepbound, and Foundayo consultations, alongside HRT, TRT, and longevity add-ons. It openly names both its pharmacy partner and its clinical network — well above the typical transparency floor — and is available in all 50 states, cash-pay only. Compounded semaglutide starts at $229/month and tirzepatide at $279/month.

Read our full AVARA Rx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

AVARA Rx

What we like

  • Names its pharmacy partner (DiRx Health, Ft Lauderdale FL) — buyers can independently verify its licensure
  • Names its clinical network (Beluga Health) — you can research the platform handling your prescriptions
  • All 50 states explicitly listed on the FAQ — uncommon vs peers that just say 'nationwide'
  • Patient-friendly refunds — full refund if a provider disqualifies you, partial if a weaker dose is prescribed
  • LegitScript verification badge displayed; pharmacy claims NABP-accredited facilities
  • Brand consultations (Wegovy, Wegovy pill, Zepbound, Foundayo) available alongside compounded options
  • Adjunct HRT, TRT, and longevity stack (Sermorelin, NAD+, Glutathione) for a broader wellness platform

Watch-outs

  • Operating legal entity not disclosed — only a Sheridan, WY registered-agent-style address surfaced
  • Dose pricing not itemized — only 'starting at $229' semaglutide and 'starting at $279' tirzepatide
  • LegitScript certification number not shown — badge only, so no direct lookup
  • No named medical director (Beluga Health is the network, not a named MD)
  • Lab work requirements not specified, and consultation fee not broken out from medication cost
  • Insurance not accepted — cash-pay only; HSA/FSA eligibility not confirmed
  • Mid-tier pricing ($229/$279) vs lower-priced compounded peers ($99–$179)

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out AVARA Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. AVARA Rx remains a solid alternative, especially if you're looking for 50-state compounded GLP-1 with named pharmacy and clinical network.

Choose AVARA Rx if…

You want 50-state compounded GLP-1 with named pharmacy and clinical network and a starting price around $229/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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AVARA Rx vs NewSelf: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.