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AskRx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
AskRx logo

AskRx

7.4
★★★3.7/5

Best for: People who want a brand-name-only GLP-1 prescriber routing to NovoCare or LillyDirect.

Visit AskRx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

AskRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

AskRx

0.25-0.5 mg (new patient)Brand-name
$199/mo
semaglutide
all dosesBrand-name
$349/mo
semaglutide
2.5 mgBrand-name
$299/mo
tirzepatide
7.5 mg+Brand-name
$449/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

AskRx

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

AskRx

7.4/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

8.0A
vs
B
8.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureAskRxNewSelf
Starting Price$199/mo$100/mo
Features8 features6 features
States Available5049
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About AskRx

AskRx is a US telehealth platform whose board-certified physicians exclusively prescribe FDA-approved, brand-name GLP-1 medications for weight loss - no compounded drugs. Offerings include the Wegovy pen and pill (semaglutide) and Zepbound (tirzepatide). AskRx does not dispense, compound, or sell medication; prescriptions are routed to manufacturer pharmacies such as NovoCare and LillyDirect at the patient's choice. A physician subscription runs $99-149/mo and medication is billed separately. LegitScript approved, HIPAA compliant, all 50 states. Subscription may be HSA/FSA eligible.

Read our full AskRx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

AskRx

What we like

  • Prescribes only FDA-approved brand-name GLP-1s, no compounded drugs
  • LegitScript approved and HIPAA compliant
  • Board-certified physicians trained in obesity medicine
  • Transparent dose-based pricing published on site
  • Available in all 50 states
  • Physician subscription may be HSA/FSA eligible

Watch-outs

  • Cash-pay model; medication cost billed separately by the pharmacy
  • Does not dispense medication itself, so fulfillment depends on third-party pharmacies
  • No compounded lower-cost alternative offered
  • Specific list of supported states is not published

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out AskRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. AskRx remains a solid alternative, especially if you're looking for People who want a brand-name-only GLP-1 prescriber routing to NovoCare or LillyDirect..

Choose AskRx if…

You want People who want a brand-name-only GLP-1 prescriber routing to NovoCare or LillyDirect. and a starting price around $199/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Synergy Rx

Broadest drug catalog in the Lion MD white-label cluster

8.1

RxSpan MD

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8.0

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Oral-lozenge compounded GLP-1 access

AskRx vs NewSelf: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.