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Ascend Medical vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Ascend Medical logo

Ascend Medical

6.9
★★★3.5/5

Best for: Georgia or Texas residents wanting medical weight loss inside virtual primary care.

Visit Ascend Medical
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Ascend Medical and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Ascend Medical

Pricing not publicly listed.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Ascend Medical

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Ascend Medical

6.9/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

6.5A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.9A
vs
B
7.9

Features & Coverage

FeatureAscend MedicalNewSelf
Starting Price$100/mo
Features8 features6 features
States Available249
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Ascend Medical

Ascend Medical is a virtual-first whole-person primary care practice that includes a Medical Weight Loss program among its services (alongside primary care, mental health, women's and men's health, diabetes care and health coaching). It is staffed by licensed MDs, DOs, NPs and PAs. Services are currently offered only to residents of Georgia and Texas. The site markets medical weight loss and metabolic health but does not publicly list specific GLP-1 products, branded-vs-compounded status, or pricing; those details require contacting the practice. Distinct from the company Ascend Vitality.

Read our full Ascend Medical review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Ascend Medical

What we like

  • Whole-person virtual primary care that includes a medical weight loss program
  • Staffed by licensed MDs, DOs, NPs and PAs
  • Integrates weight loss with primary, mental health and diabetes care
  • Clear state availability (Georgia and Texas)

Watch-outs

  • Available only in Georgia and Texas
  • Specific GLP-1 medications and branded-vs-compounded status not published
  • No pricing disclosed on public pages
  • Weight loss is one service among many, not a dedicated GLP-1 specialist

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Ascend Medical with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Ascend Medical remains a solid alternative, especially if you're looking for Georgia or Texas residents wanting medical weight loss inside virtual primary care..

Choose Ascend Medical if…

You want Georgia or Texas residents wanting medical weight loss inside virtual primary care..

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Ascend Medical vs NewSelf: FAQ

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