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ARSYNL Rx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
ARSYNL Rx logo

ARSYNL Rx

6.9
★★★3.5/5

Best for: Compounded semaglutide & tirzepatide (incl. a tirzepatide hypospray) from a veteran-founded telehealth

Visit ARSYNL Rx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

ARSYNL Rx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

ARSYNL Rx

Pricing not publicly listed.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

ARSYNL Rx

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

ARSYNL Rx

6.9/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.4A
vs
B
7.9

Features & Coverage

FeatureARSYNL RxNewSelf
Starting Price$100/mo
Features8 features6 features
States AvailableNot disclosed49
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About ARSYNL Rx

ARSYNL Rx is a veteran-founded multi-service telehealth platform offering compounded GLP-1 weight-loss treatment — compounded semaglutide and tirzepatide, including a needle-free tirzepatide hypospray — alongside hair restoration, testosterone therapy, sexual health, and longevity care. Treatment is clinician-prescribed and shipped discreetly to your home. Specific pricing appears on each product page after you select a therapy.

Read our full ARSYNL Rx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

ARSYNL Rx

What we like

  • Offers compounded semaglutide and tirzepatide, including a needle-free tirzepatide hypospray option
  • Veteran-founded telehealth with clinician-prescribed, personalized treatment
  • Multi-service platform — also covers hair restoration, TRT, sexual health, and longevity
  • Medications shipped discreetly to your home

Watch-outs

  • Pricing is not shown until you select a product (product pages sit behind a bot-verification gate)
  • Compounded GLP-1s are not FDA-approved finished products
  • Compounding pharmacy partner and exact state coverage are not disclosed on the site
  • No LegitScript certification visible on the accessible pages

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out ARSYNL Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. ARSYNL Rx remains a solid alternative, especially if you're looking for Compounded semaglutide & tirzepatide (incl. a tirzepatide hypospray) from a veteran-founded telehealth.

Choose ARSYNL Rx if…

You want Compounded semaglutide & tirzepatide (incl. a tirzepatide hypospray) from a veteran-founded telehealth.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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ARSYNL Rx vs NewSelf: FAQ

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