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AM Rx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
AM Rx logo

AM Rx

6.0
★★★☆☆3/5

Best for: brand-name GLP-1 via insurance — review its regulatory warnings first

Visit AM Rx
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

AM Rx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $151/mo, and NewSelf edges ahead overall (8.3 vs 6.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

AM Rx

Brand GLP-1 with insuranceBrand-name
$25/mo
semaglutide

As low as $25/mo with insurance coordination; a separate AM Rx membership is still required.

Compounded Semaglutide (quarterly)Compounded
$151/mo
semaglutide

Medication only ($151/mo when purchased quarterly); the recurring AM Rx membership is billed on top.

Required AM Rx membership (subscription, separate from medication)membership subscription
$135$39/mo
Save 71% right now

$135/mo membership, $39 for the first month, renewing monthly. Medication is billed separately.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

AM Rx

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

AM Rx

6.0/10

Overall

NewSelf

8.3/10

Value25%

6.0A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

6.0A
vs
B
8.0

Trust & Safety15%

4.3A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

4.9A
vs
B
7.9

Features & Coverage

FeatureAM RxNewSelf
Starting Price$151/mo$100/mo
Features7 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA Warnings3 warnings1 warning

About AM Rx

AM Rx (getamrx.com) is a telehealth platform operated by FitRX, LLC (also operates Zealthy and FitRx). Offers compounded semaglutide from $151/mo quarterly and brand-name GLP-1s (Ozempic, Wegovy, Zepbound, Mounjaro) with insurance coordination as low as $25/mo. Video and async consultations available. HSA/FSA accepted.

Read our full AM Rx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

AM Rx

What we like

  • Insurance coordination for brand-name GLP-1s — as low as $25/mo
  • All four major brand-name GLP-1s available (Ozempic, Wegovy, Zepbound, Mounjaro)
  • HSA and FSA accepted
  • Video visits available with providers averaging 10+ years' experience
  • Compounded semaglutide from $151/mo on the quarterly plan

Watch-outs

  • Active FTC/DOJ lawsuit over deceptive billing and subscription practices
  • Two FDA warning letters (Sept 2025, Feb 2026) for misbranding compounded GLP-1s
  • Novo Nordisk false-advertising lawsuit (Aug 2025)
  • Parent company Zealthy holds a BBB D- rating with 2,370+ complaints
  • Trustpilot 2.0/5, with 85% one-star reviews citing billing disputes and unreachable support
  • No named pharmacy partners, no LegitScript certification, and no FDA compounding disclaimer on the site
  • Requires a separate recurring membership ($135/mo standard, $39 first month) on top of the medication price

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out AM Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. AM Rx remains a solid alternative, especially if you're looking for brand-name GLP-1 via insurance — review its regulatory warnings first.

Choose AM Rx if…

You want brand-name GLP-1 via insurance — review its regulatory warnings first and a starting price around $151/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Mainstream telehealth GLP-1 access

8.2

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Compounded GLP-1/GIP combo on a yearly plan with free shipping

6.9

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Nationwide compounded GLP-1 availability including Puerto Rico

AM Rx vs NewSelf: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $151/mo for AM Rx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 6.0/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, AM Rx is a better fit if you want brand-name GLP-1 via insurance — review its regulatory warnings first.
NewSelf lists availability in 49 states, while AM Rx's state list is not publicly listed.
Neither AM Rx nor NewSelf is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, AM Rx is cheaper at $25/mo versus $100/mo at NewSelf.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring AM Rx and NewSelf head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.