Amazon One Medical vs Zeuss
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →
Zeuss
Best for: the only one-time-purchase, no-subscription compounded GLP-1 model
Visit Zeuss →Amazon One Medical and Zeuss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Zeuss starts lower at $125/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Zeuss
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Zeuss
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Zeuss
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Zeuss |
|---|---|---|
| Starting Price | $149/mo | ✓$125/mo |
| Features | ✓6 features | 4 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Zeuss
Zeuss is a multi-vertical telehealth platform offering compounded semaglutide and tirzepatide for weight loss alongside TRT, HRT, skin, and hair services. Its genuine differentiator is a no-subscription, one-time-purchase model — no auto-renewals or memberships, with a full refund if a physician can't prescribe. Bundled pricing covers provider review, medication, and cold-chain shipping; GLP-1 starts at $125/mo and tirzepatide at $175/mo.
Read our full Zeuss review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Zeuss
What we like
- One-time-purchase model with no subscription — genuinely rare among DTC GLP-1 providers
- Publishes the FDA compounded-medication disclaimer
- Names both 503A and 503B compounding pathways — uncommon transparency
- Bundled pricing covers provider review, meds, and cold-chain shipping with no hidden fees
- Full refund if a physician can't prescribe
- $125/mo starting price, competitive with the broader DTC market
- Temperature-controlled cold-chain shipping disclosed
- Gender-segmented Body services for patients who prefer male- or female-focused framing
Watch-outs
- 503A pharmacy partner not named (only generic '503A and 503B state-licensed' framing)
- LegitScript certification not mentioned
- No named medical director or physician leadership
- Full states-served list not disclosed
- Corporate legal entity not disclosed
- Governing law and arbitration venue not disclosed
- GLP-1 pages live at awkward URLs (/services/body-for-him/ and /services/body-for-her/)
- Corporate physical address not disclosed
Our Verdict
Amazon One Medical edges out Zeuss with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Zeuss remains a solid alternative, especially if you're looking for the only one-time-purchase, no-subscription compounded GLP-1 model.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Choose Zeuss if…
You want the only one-time-purchase, no-subscription compounded GLP-1 model and a starting price around $125/mo.
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TrimRx
Best overall value
From $135/mo
Get started →Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →PeterMD
Men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy
From $105/mo
Get started →Amazon One Medical vs Zeuss: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.