Amazon One Medical vs Vitals Vault
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.8 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; Vitals Vault $157/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states (Vitals Vault doesn't publish a state list)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Vitals Vault: medication, shipping (not included: clinician visits)
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
Vitals Vault
Best for low-cost compounded GLP-1s billed every 4 weeks, from a lab-testing company with optional bloodwork
semaglutide
$157
billed every 4 weeks
Our score 7.8/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Vitals Vault
Price
Semaglutide / month
Not listed
$157/mo
billed every 4 weeks
Tirzepatide / month
Not listed
$169/mo
billed every 4 weeks
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, shipping
Not included: clinician visits
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None stated; the medication plan renews every 4 weeks until canceled
Refunds
Not disclosed
$20 review refunded if not prescribed; medication already dispensed, shipped or made available is non-refundable unless required by law
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
November 2026
Every dose and plan: Amazon One Medical · Vitals Vault
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Vitals Vault doesn't price
- Publishes its full state list (50 states)
- Price includes clinician visits; Vitals Vault's doesn't
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose Vitals Vault if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Prices are shown on each treatment page before you start
What to weigh up
- No published state list; confirm yours at signup
- Price doesn't include clinician visits
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Vitals Vault
7.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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CoreAge Rx
Lowest-price compounded semaglutide and tirzepatide with one flat price at every dose
Read full review →From $79/mo (“starting at” price)
Get started →From $79/mo (sale price)
Get started →Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →Amazon One Medical vs Vitals Vault: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and Vitals Vault head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
- Vitals Vault vs Vytora Health
Or see the full category ranking, or alternatives to Amazon One Medical and Vitals Vault.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.