Amazon One Medical vs Refills
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savingsStarting at $25/mo
Refills
Best for patients seeking a single account across multiple cash-pay telehealth categories (GLP-1 + ED + hair growth) and willing to verify state coverage + steady-state pricing during the intake before committingSide-by-Side Comparison
| Feature | Amazon One Medical | Refills |
|---|---|---|
| Overall Score | ✓8.7/10 | 6.9/10 |
| Starting Price | $25/mo | — |
| Editorial Rating | ✓4.4 ★ /5 | 3.5 ★ /5 |
| Features | 6 features | ✓7 features |
| States Available | ✓50 | 0 |
| Compounded | — | — |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Amazon One Medical
Pros
- ✓$1/day ($25/month) with insurance and the automatically-applied Lilly manufacturer-sponsored coupon — the cheapest brand-name Foundayo channel we've seen
- ✓Same-day delivery in nearly 3,000 US cities and towns at launch, expanding to 4,500 by year-end 2026 — most aggressive delivery footprint of any GLP-1 distribution channel
- ✓In-office, licensed-pharmacist-supported kiosks at select One Medical locations let patients walk out of an appointment with their Foundayo in hand — bypasses pharmacy lines entirely
- ✓Cash-pay $5/day ($149/month) is competitive with Ro and GoodRx for the same FDA-approved brand-name product
- ✓Real-time medication availability + transparent pricing + automatic manufacturer coupon application before checkout
- ✓Has been delivering GLP-1 medications since 2021 — operational track record on cold-chain biologic logistics
- ✓24/7 access to licensed pharmacists for clinical questions
Cons
- ✗Headline $25/month Foundayo price requires both insurance coverage AND the Lilly Savings Card — uninsured patients pay the $149/month cash price
- ✗Same-day delivery is geographically gated — outside the ~3,000 cities, delivery falls back to next-day, two-day, or three-day depending on remoteness
- ✗Pricing is set by manufacturer (Lilly, Novo Nordisk) savings programs and can change at any time
- ✗Does not offer compounded semaglutide or tirzepatide — brand-name only (Foundayo, Wegovy, Zepbound)
- ✗Wegovy / Zepbound pricing is not publicly disclosed on the Amazon One Medical landing page — it depends on insurance coverage at the prescribing visit. Plan to review final pricing at checkout before committing
- ✗One Medical clinical visits accept insurance, but copays/deductibles still apply for the Scheduled Visit; cash-pay visit pricing is also disclosed on enrollment
Refills
Pros
- ✓LegitScript Certified seal verbatim ('LegitScript certified online pharmacy' alt text on the certification logo)
- ✓Provider claims operation across all 50 US states (with disclosed exclusions)
- ✓Multi-category telehealth platform (GLP-1 weight loss + ED + hair growth + daily wellness) — single-account convenience for patients seeking multiple modalities
- ✓Free shipping disclosed publicly
- ✓No insurance needed framing — cash-pay transparency
- ✓Webflow-hosted modern marketing site with structured Organization JSON-LD (signals operational maturity)
Cons
- ✗Steady-state monthly pricing for compounded semaglutide and tirzepatide NOT disclosed publicly — gated behind intake
- ✗Specific legal entity name + state of incorporation NOT publicly disclosed
- ✗Specific partner compounding pharmacy NOT named
- ✗Excluded state/region list (per the 'does not service the' caveat in their 50-state claim) NOT visible in marketing copy — patients should verify state coverage during intake
- ✗Brand-name GLP-1 lineup (Wegovy/Zepbound/Mounjaro/Ozempic/Foundayo) NOT addressed — compounded only
- ✗Lab work + ongoing-care touchpoints NOT clearly disclosed
- ✗Multi-category model (also operating in ED + hair) signals broad direct-to-consumer telehealth rather than a GLP-1-specialist platform
Our Verdict
Amazon One Medical edges out Refills with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Refills remains a solid alternative, especially if you're looking for patients seeking a single account across multiple cash-pay telehealth categories (GLP-1 + ED + hair growth) and willing to verify state coverage + steady-state pricing during the intake before committing.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.