Amazon One Medical vs Refills
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →
Refills
Best for: single account across GLP-1, ED and hair-growth telehealth
Visit Refills →Amazon One Medical and Refills are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts at $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Refills
Pricing not publicly listed.
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Refills
What the monthly price covers
Medication
Not disclosed
Provider visits
Not disclosed
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Refills
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Refills |
|---|---|---|
| Starting Price | $149/mo | — |
| Features | 6 features | 6 features |
| States Available | 50 | Not disclosed |
| Compounded | — | — |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Refills
Refills (refills.com) is a LegitScript-certified online pharmacy and telehealth platform offering compounded GLP-1 weight-loss prescriptions (semaglutide, tirzepatide) alongside ED, hair growth, and daily wellness treatments. Provider claims operation across all 50 US states (with documented exclusion of certain regions). Pricing is gated behind the intake; site is Webflow-hosted with dynamic content. Free shipping; no insurance needed.
Read our full Refills review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Refills
What we like
- LegitScript Certified online pharmacy
- Claims operation across all 50 states (with some exclusions)
- Multi-category platform (weight loss + ED + hair growth + wellness) — single account for multiple treatments
- Free shipping disclosed publicly
- Cash-pay, no insurance needed
Watch-outs
- Ongoing monthly pricing for compounded semaglutide and tirzepatide not shown until after intake
- Legal entity name and state of incorporation not disclosed
- Compounding pharmacy partner not named
- Excluded states not listed in marketing copy — verify coverage during intake
- Compounded only — no brand-name GLP-1 (Wegovy, Zepbound, Mounjaro, Ozempic, Foundayo)
- Lab work and ongoing-care touchpoints not clearly disclosed
Our Verdict
Amazon One Medical edges out Refills with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Refills remains a solid alternative, especially if you're looking for single account across GLP-1, ED and hair-growth telehealth.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Choose Refills if…
You want single account across GLP-1, ED and hair-growth telehealth.
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Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Patients who want the option to switch between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →Amazon One Medical vs Refills: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.