Amazon One Medical vs PrescribedRX
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →
PrescribedRX
Best for: people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brand
Visit PrescribedRX →Amazon One Medical and PrescribedRX are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $189/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
PrescribedRX
Monthly plan $189/mo; as low as $176/mo on the 3-month plan ($526)
Monthly plan $276/mo; as low as $233/mo on the 3-month plan ($697)
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
PrescribedRX
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
PrescribedRX
6.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | PrescribedRX |
|---|---|---|
| Starting Price | ✓$149/mo | $189/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | — | — |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About PrescribedRX
PrescribedRX is a multi-condition telehealth brand (TRT, longevity, hair loss, sexual health and weight loss) that prescribes compounded GLP-1 injectables for weight loss: semaglutide at $189/month and tirzepatide at $276/month, dropping to $176 and $233/month on a 3-month plan. Care is delivered online with licensed US-provider oversight and monthly home delivery, and the site is bilingual (English/Spanish) with Florida/Palm Beach-focused offers. It runs an in-house affiliate program but does not name its compounding pharmacies or publish the states it serves.
Read our full PrescribedRX review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
PrescribedRX
What we like
- Compounded semaglutide ($189/mo) and tirzepatide ($276/mo) injectables, with lower per-month pricing on the 3-month plans ($176 and $233/mo)
- Clear, upfront plan pages showing monthly and multi-month pricing with no surprise fees
- Care from licensed US providers with monthly home delivery and ongoing dose support
- Bilingual English/Spanish site and a broader telehealth menu (TRT, longevity, hair, sexual health) for people who want more than weight loss
Watch-outs
- Doesn't publish the states it serves — you only learn eligibility after starting the intake
- Compounding pharmacies aren't named on the site
- Mid-range pricing — cheaper compounded GLP-1 options exist and the 3-month discount is modest
- Compounded semaglutide and tirzepatide injectables only — no brand-name or oral options
- Self-hosted affiliate program (not a vetted network); Florida/Palm Beach framing suggests a regional lean
Our Verdict
Amazon One Medical edges out PrescribedRX with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. PrescribedRX remains a solid alternative, especially if you're looking for people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brand.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Choose PrescribedRX if…
You want people who want compounded GLP-1 weight loss inside a broader men's and women's telehealth brand and a starting price around $189/mo.
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Get started →Amazon One Medical vs PrescribedRX: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.