Amazon One Medical vs MyStart Health
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; MyStart Health $299/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states (MyStart Health doesn't publish a state list)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); MyStart Health: medication, clinician visits, shipping, labs
- Safety
- FDA warning letters on record: Amazon One Medical none, MyStart Health 1
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
MyStart Health
Best for fastest compounded GLP-1 onboarding with a price lock
semaglutide
$299
Our score 7.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
MyStart Health
Price
Semaglutide / month
Not listed
$299/mo
Tirzepatide / month
Not listed
$299/mo
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping, labs
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None stated. Monthly plans bill each month; 3-month plans bill every 3 months and ship the full supply at once.
Refunds
Not disclosed
Refund Policy: 'Once an order has been shipped, it cannot be canceled and no refund will be issued under any circumstances.' Full refund only if a provider finds you ineligible or you cancel before the pharmacy fulfills the order.
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
October 2026
October 2026
Every dose and plan: Amazon One Medical · MyStart Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which MyStart Health doesn't price
- Publishes its full state list (50 states)
- No FDA warning letters on record (MyStart Health has 1)
What to weigh up
- Price doesn't include medication and labs
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose MyStart Health if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Price includes medication and labs; Amazon One Medical's doesn't
- Fast onboarding: roughly 5-minute intake, 24-hour prescription turnaround, 2–4 day shipping
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
MyStart Health
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Amazon One Medical vs MyStart Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.