Amazon One Medical vs Meli Health
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →
Meli Health
Best for: people who want compounded semaglutide or tirzepatide from a service that names its pharmacy
Visit Meli Health →Amazon One Medical and Meli Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $229/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Meli Health
$147 for the first month, then $229 a month, as checkout states. Checkout pre-selects a $29.95 priority review add-on that you can untick
$179 for the first month, then $299 a month, as checkout states. Checkout pre-selects a $29.95 priority review add-on that you can untick
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Meli Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Meli Health
6.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Meli Health |
|---|---|---|
| Starting Price | ✓$149/mo | $229/mo |
| Features | 6 features | 6 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Meli Health
Meli Health is a telehealth company that sells compounded semaglutide and tirzepatide, prescribed by clinicians in the LocumTele network and filled by Rush Pharmacy, alongside NAD+, sermorelin and other wellness treatments. The first month costs $147 for semaglutide or $179 for tirzepatide, then $229 or $299 a month. It serves 49 states but not California.
Read our full Meli Health review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Meli Health
What we like
- Names both its clinician network, LocumTele, and the compounding pharmacy that fills orders, Rush Pharmacy
- Treatment pages show the first-month and ongoing monthly price before you start the intake
- Your card is pre-authorized and charged only if a physician prescribes treatment
- The monthly price includes the provider consultation, medication and free expedited shipping
- Month-to-month plan you can cancel from your patient portal or by email
- Intake and clinician review happen online, with no in-person visit
Watch-outs
- The results screen says your plan is approved, with a countdown timer, before any clinician has reviewed your answers
- Checkout pre-selects a $29.95 priority review add-on, so you must untick it to pay the advertised price
- The $147 and $179 prices are first-month offers; plans renew at $229 and $299 a month
- Checkout advertises a money-back guarantee, but the refund policy rules out refunds once medication is dispensed
- Support is by email only, though the site advertises unlimited 24/7 support
- You must cancel at least 48 hours before your billing date to avoid the next charge, with no prorated refunds
- The LegitScript seal on the site could not be matched to a LegitScript record, and there is no Trustpilot profile
- Not available in California
Our Verdict
Amazon One Medical edges out Meli Health with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Meli Health remains a solid alternative, especially if you're looking for people who want compounded semaglutide or tirzepatide from a service that names its pharmacy.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Choose Meli Health if…
You want people who want compounded semaglutide or tirzepatide from a service that names its pharmacy and a starting price around $229/mo.
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MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Oak
Compounded semaglutide and tirzepatide at a flat monthly price
From $133/mo
Get started →Amazon One Medical vs Meli Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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