Amazon One Medical vs Medi-Weightloss
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →
Medi-Weightloss
Best for: Patients wanting in-person physician-supervised GLP-1 care with insurance/HSA use
Visit Medi-Weightloss →Amazon One Medical and Medi-Weightloss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Medi-Weightloss
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Medi-Weightloss
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Medi-Weightloss
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Medi-Weightloss |
|---|---|---|
| Starting Price | ✓$149/mo | $199/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | — | — |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Medi-Weightloss
Medi-Weightloss is an established physician-supervised weight-loss brand with 130-plus locations nationwide plus telehealth. Its GLP-1 program prescribes branded Wegovy and Zepbound as well as compounded semaglutide and compounded tirzepatide, alongside older agents like phentermine. Programs are evidence-based, with body-composition analysis and personalized plans. A new-patient visit runs about $199 and includes a medical assessment, labs and GLP-1 eligibility review; ongoing medication costs depend on the plan. Insurance is accepted at many locations and HSA/FSA accounts are welcome.
Read our full Medi-Weightloss review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Medi-Weightloss
What we like
- Both branded (Wegovy, Zepbound) and compounded semaglutide/tirzepatide
- Established brand with 130+ physician-supervised locations nationwide
- Telehealth plus in-person clinic options
- Accepts insurance at many locations; HSA/FSA welcome
- Includes body-composition analysis and personalized plans
Watch-outs
- Ongoing medication pricing not transparently posted; varies by plan
- $199 new-patient visit fee before medication costs
- Frequent (often weekly) visits expected for some patients
- Compounded products are not FDA-approved or evaluated
Our Verdict
Amazon One Medical edges out Medi-Weightloss with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Medi-Weightloss remains a solid alternative, especially if you're looking for Patients wanting in-person physician-supervised GLP-1 care with insurance/HSA use.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Choose Medi-Weightloss if…
You want Patients wanting in-person physician-supervised GLP-1 care with insurance/HSA use and a starting price around $199/mo.
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Get started →Amazon One Medical vs Medi-Weightloss: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.