Amazon One Medical vs Knownwell
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.7 out of 10), and Knownwell costs less for brand-name Zepbound / Mounjaro (about $299 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Knownwell $299/mo vs Amazon One Medical $299/mo for brand-name Zepbound / Mounjaro (standing prices, no prepay or separate membership listed · about $299 a year less with Knownwell · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Both serve the same 50 states
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Knownwell: not stated
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Zepbound / Mounjaro
$299
billed every 4 weeks
Our score 8.5/10
Knownwell
Best for branded GLP-1s with obesity-medicine oversight and insurance options
Brand-name Zepbound / Mounjaro
$299
Our score 7.7/10
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Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Knownwell
Price
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Better on this row: $299/mo
Brand Zepbound / Mounjaro / year (modeled)
$3,887
13 charges
Better on this row: $3,588
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Zepbound / Mounjaro, Wegovy / Ozempic, Wegovy pill / Rybelsus, Foundayo
Zepbound / Mounjaro
Included in the price
Clinician visits, shipping
Not included: medication, labs
Not disclosed
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
Lab work
Required
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: Amazon One Medical · Knownwell
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which Knownwell doesn't price
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
- Brand-name Wegovy, Zepbound and Foundayo prescribed by One Medical clinicians and filled by Amazon Pharmacy
What to weigh up
- About $299 a year more than Knownwell for brand-name Zepbound / Mounjaro (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose Knownwell if…
- About $299 a year less than Amazon One Medical for brand-name Zepbound / Mounjaro at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Co-founded by obesity-medicine specialist Dr. Angela Fitch
- Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
What to weigh up
- Specific self-pay monthly medication prices not transparently posted
- In-person clinics limited to four metro areas
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Knownwell
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →From $139/mo
Get started →Amazon One Medical vs Knownwell: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.