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Amazon One Medical vs Ecka Health

In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; Ecka Health $99/mo for compounded semaglutide (different medications, so not compared on price)
Coverage
Amazon One Medical 50 states (Ecka Health doesn't publish a state list)
Included
Amazon One Medical: clinician visits, shipping (not included: medication, labs); Ecka Health: not stated

How we compare providers

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

Ecka Health logo

Ecka Health

Best for compounded GLP-1s or Zepbound from a named physician group, if you can wait until sign-up to see prices

semaglutide

$99/mo

starting dose

Our score 7.1/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Amazon One Medical

Ecka Health

Price

Semaglutide / month

Not listed

$99/mo

starting dose

Tirzepatide / month

Not listed

$199/mo

starting dose

Brand Wegovy / Ozempic / month

$199/mo

billed every 4 weeks

Not listed

Brand Zepbound / Mounjaro / month

$299/mo

billed every 4 weeks

Not listed

Brand Wegovy pill / Rybelsus / month

$149/mo

Not listed

Brand Foundayo / month

$149/mo

Not listed

Coverage

State availability

50 states

List not published

Oral option listed

Yes

Not listed

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Not listed

Included in the price

Clinician visits, shipping

Not included: medication, labs

Not disclosed

Terms & safety

Price shown

Before intake

Plan quoted after intake; a price is published

Lab work

Required

Not disclosed

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

Subscription terms are disclosed at enrollment; the Terms allow purchase periods of up to 6 or 12 months

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

November 2026

Every dose and plan: Amazon One Medical · Ecka Health

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Amazon One Medical logo

Choose Amazon One Medical if…

  • Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Ecka Health doesn't price
  • Publishes its full state list (50 states)
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible

What to weigh up

  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
  • You must provide recent lab results (kidney function and glucose or A1c), bought separately if you have none
Ecka Health logo

Choose Ecka Health if…

  • Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
  • Names its physician group, Arora Health & Aesthetics, and its two doctors
  • LegitScript seal served from LegitScript's own site

What to weigh up

  • No published state list; confirm yours at signup
  • Full prices and plan terms appear only after you create an account and finish the intake

Amazon One Medical and Ecka Health in context

No medication appears on both price lists, so there is no fair price comparison to make. Amazon One Medical lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, while Ecka Health lists compounded semaglutide and compounded tirzepatide. If you have not settled on a medication yet, our Wegovy page and semaglutide page cover what each one is approved for and what it costs. In our scoring, Amazon One Medical is at 8.5 and Ecka Health at 7.1 out of 10.

Amazon One Medical prices only brand-name medication, while Ecka Health sells compounded versions prepared by a pharmacy. That is a bigger difference than the monthly figure suggests, and our compounded vs brand-name decision guide walks through it. Only Amazon One Medical lists a pill (brand-name Wegovy pill / Rybelsus). If avoiding injections is the point, read our Wegovy pill guide before choosing on price. Amazon One Medical publishes where it ships (50 states); Ecka Health does not publish a state list, so confirm yours at intake or start from providers by state.

The next head-to-head for Amazon One Medical is Amazon One Medical vs Eden; Eden sells semaglutide and tirzepatide and lists 50 states. For Ecka Health, it is Ecka Health vs Vytora Health; Vytora Health sells semaglutide and tirzepatide and lists 50 states + DC. If neither fits, the wider shortlists are alternatives to Amazon One Medical and alternatives to Ecka Health.

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Ecka Health

7.1/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

8.0A
vs
B
6.5

Trust & Safety15%

8.8A
vs
B
6.5

Accessibility10%

9.5A
vs
B
7.0

Support10%

8.0A
vs
B
6.5

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Amazon One Medical vs Ecka Health: FAQ

Amazon One Medical scores higher overall at 8.5/10 versus 7.1/10, and is particularly strong for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery. That said, Ecka Health is a better fit if you want compounded GLP-1s or Zepbound from a named physician group, if you can wait until sign-up to see prices.
Neither Amazon One Medical nor Ecka Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
Not at a published price. Amazon One Medical lists brand-name Foundayo, brand-name Wegovy pill / Rybelsus, brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro; Ecka Health lists compounded semaglutide, compounded tirzepatide.
Amazon One Medical publishes 50 states. Ecka Health doesn't publish a state list. Where a list isn't published, confirm your state during sign-up before paying.
Amazon One Medical doesn't state its cancellation terms. Ecka Health: cancel anytime (yes), minimum commitment (Subscription terms are disclosed at enrollment; the Terms allow purchase periods of up to 6 or 12 months), early-cancellation fee (not disclosed). Check the provider's own terms before you buy.

Key terms, explained

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Continue exploring Amazon One Medical and Ecka Health head-to-heads in the same category.

Or see the full category ranking, or alternatives to Amazon One Medical and Ecka Health.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.