Amazon One Medical vs Aspen
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.6 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; Aspen $179/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states; Aspen 50 states + DC (only Aspen: District of Columbia)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Aspen: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
Aspen
Best for LegitScript-certified compounded GLP-1s with flat dosing
semaglutide
$179
Our score 7.6/10
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Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Aspen
Price
Semaglutide / month
Not listed
$179/mo
Tirzepatide / month
Not listed
$179/mo
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
50 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Better on this row: Not required
Video visit
Not disclosed
Not required
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Show where they differ by stateHide state lists
Only Aspen (DC)
- District of Columbia
Every dose and plan: Amazon One Medical · Aspen
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Aspen doesn't price
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
- Brand-name Wegovy, Zepbound and Foundayo prescribed by One Medical clinicians and filled by Amazon Pharmacy
What to weigh up
- Not available in District of Columbia
- Price doesn't include medication
Choose Aspen if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Serves District of Columbia, where Amazon One Medical doesn't
- Price includes medication; Amazon One Medical's doesn't
What to weigh up
- Compounded semaglutide and tirzepatide only — no brand Wegovy, Zepbound or Ozempic — and compounded GLP-1s aren't FDA-approved
- Even the "monthly" plan requires a 3-month commitment, with three months of medication shipped and billed upfront
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Aspen
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →Amazon One Medical vs Aspen: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
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- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
- Aspen vs Vytora Health
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.