50 Stars Health vs Amazon One Medical
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.2 out of 10).
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Key differences
- Price
- 50 Stars Health $146/mo for compounded semaglutide; Amazon One Medical $199/mo for brand-name Wegovy / Ozempic (different medications, so not compared on price)
- Coverage
- 50 Stars Health 44 states; Amazon One Medical 50 states (only Amazon One Medical: Alabama, Arkansas, California and 3 more)
- Included
- 50 Stars Health: medication, clinician visits, shipping; Amazon One Medical: clinician visits, shipping (not included: medication, labs)
50 Stars Health
Best for flat-price compounded semaglutide or tirzepatide with consult, medication and shipping in one price
semaglutide
$146
$124 first month · starting dose
Our score 7.2/10
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
50 Stars Health
Amazon One Medical
Price
Semaglutide / month
$146/mo
$124 first month · starting dose
Not listed
Tirzepatide / month
$220/mo
$183 first month · starting dose
Not listed
Brand Wegovy / Ozempic / month
Not listed
$199/mo
billed every 4 weeks
Brand Zepbound / Mounjaro / month
Not listed
$299/mo
billed every 4 weeks
Brand Wegovy pill / Rybelsus / month
Not listed
$149/mo
Brand Foundayo / month
Not listed
$149/mo
Coverage
State availability
44 states
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Medication, clinician visits, shipping
Clinician visits, shipping
Not included: medication, labs
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not disclosed
Required
Cancel anytime
Yes
Not disclosed
Minimum commitment
Auto-renewing 1-, 3- or 6-month plan
Not disclosed
Refunds
Not typically offered; partial refunds at the company's discretion for any non-dispensed portion
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Amazon One Medical (6 states)
- Alabama
- Arkansas
- California
- Indiana
- South Carolina
- West Virginia
Every dose and plan: 50 Stars Health · Amazon One Medical
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose 50 Stars Health if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
What to weigh up
- Not available in 6 states that Amazon One Medical serves
- GLP-1s not offered in every state (44 states plus Puerto Rico)
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which 50 Stars Health doesn't price
- Serves 6 states that 50 Stars Health doesn't
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
50 Stars Health
7.2/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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From $139/mo (4-month plan rate)
Get started →Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo (+ required membership)
Get started →50 Stars Health vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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- Amazon One Medical vs Collective
Or see the full category ranking, or alternatives to 50 Stars Health and Amazon One Medical.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.