1st Optimal vs Roboclinic
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Roboclinic
Best for: AI-first GLP-1 care with all-in compounded semaglutide and tirzepatide
Visit Roboclinic →1st Optimal and Roboclinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $179/mo, and Roboclinic edges ahead overall (7.7 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Roboclinic
'$179/m' 12-month plan price (strikethrough from $249); month-to-month is $299/mo, 3-month $249/mo. Live-verified 2026-07-10
Oral compounded semaglutide tablets; 12-month plan $249/mo, 3-month $279/mo, month-to-month $299/mo. Live-verified 2026-07-10
'$299/m' 12-month plan price (strikethrough from $399); month-to-month is $399/mo, 3-month $349/mo. Live-verified 2026-07-10
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Roboclinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Roboclinic
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Roboclinic |
|---|---|---|
| Starting Price | ✓$99/mo | $179/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Roboclinic
Roboclinic is an AI-first telehealth platform, operated by BrickFi, Inc., that starts you with an AI health assistant and then routes you to a board-certified provider for GLP-1 weight-loss care. It sells compounded semaglutide from $179/mo (injections) or $249/mo (oral tablets) and compounded tirzepatide from $299/mo, with the consult, prescription, and delivery bundled into one all-in price that stays the same at every dose. Clinical review and pharmacy fulfillment run through OpenLoop Health.
Read our full Roboclinic review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Roboclinic
What we like
- Compounded semaglutide from $179/mo and tirzepatide from $299/mo on 12-month plans
- One all-in price bundles the provider consult, prescription, and delivery
- Offers both injectable and oral (tablet) compounded semaglutide
- 'Same price, every dose' means your cost does not rise as the dose increases
- AI-first intake with board-certified provider review; no insurance necessary
- LegitScript-certified; clinical care and pharmacy fulfillment coordinated through OpenLoop Health
- Cancel anytime from your profile
Watch-outs
- Lowest rates require a 12-month plan; month-to-month runs $299/mo (semaglutide) to $399/mo (tirzepatide)
- Individual compounding pharmacies are not named; fulfillment is routed through OpenLoop Health
- No published per-state list; site claims 'all 50 states, restrictions apply' and gates doctor review by region
- Refunds limited to your most recent billing cycle; none for used or partially used periods
- Operated by BrickFi, Inc., a newer brand with limited independent track record
Our Verdict
Roboclinic edges out 1st Optimal with a higher overall score of 7.7/10 and is particularly strong for AI-first GLP-1 care with all-in compounded semaglutide and tirzepatide. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Roboclinic if…
You want AI-first GLP-1 care with all-in compounded semaglutide and tirzepatide and a starting price around $179/mo.
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Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →MEDVi
Switching between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →1st Optimal vs Roboclinic: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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