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1st Optimal vs Nu Image Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Nu Image Medical logo

Nu Image Medical

7.1
★★★3.6/5

Best for: mainstream telehealth GLP-1 access

Visit Nu Image Medical

1st Optimal and Nu Image Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $99/mo, and Nu Image Medical edges ahead overall (7.1 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Nu Image Medical

Injectioncompounded injection
$99/mo
semaglutide
Rapid-dissolve tablets (RDT)compounded oral
$269/mo
semaglutide
Injectioncompounded injection
$299/mo
tirzepatide
Rapid-dissolve tablets (RDT)compounded oral
$314/mo
tirzepatide

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Nu Image Medical

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Nu Image Medical

7.1/10

Value25%

6.5A
vs
B
6.5

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.0

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalNu Image Medical
Starting Price$99/mo$99/mo
Features8 features2 features
States AvailableNot disclosedNot disclosed
Compounded
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Nu Image Medical

Telehealth wellness provider offering GLP-1 medications and other prescription services.

Read our full Nu Image Medical review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Nu Image Medical

What we like

  • Both semaglutide and tirzepatide available

Watch-outs

  • Pricing not publicly disclosed

Our Verdict

Winner: Nu Image Medical

Nu Image Medical edges out 1st Optimal with a higher overall score of 7.1/10 and is particularly strong for mainstream telehealth GLP-1 access. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Nu Image Medical if…

You want mainstream telehealth GLP-1 access and a starting price around $99/mo.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

1st Optimal vs Nu Image Medical: FAQ

1st Optimal and Nu Image Medical have the same lowest ongoing monthly price of $99/mo, so price alone won't separate them — compare what each plan includes instead.
Nu Image Medical scores higher overall at 7.1/10 versus 6.7/10, and is particularly strong for mainstream telehealth GLP-1 access. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Neither 1st Optimal nor Nu Image Medical publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 1st Optimal nor Nu Image Medical is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
1st Optimal and Nu Image Medical list the same lowest price for Semaglutide: $99/mo.

Key terms, explained

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Continue exploring 1st Optimal and Nu Image Medical head-to-heads in the same category.

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