1st Optimal vs MyFastRx
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine programMyFastRx
Best for Cash-pay patients comfortable with 12-month upfront billing for the lowest compounded-GLP-1 monthly rate.Starting at $99/mo
Side-by-Side Comparison
| Feature | 1st Optimal | MyFastRx |
|---|---|---|
| Overall Score | 6.7/10 | ✓7.0/10 |
| Starting Price | — | $99/mo |
| Editorial Rating | 3.4 ★ /5 | ✓3.5 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | 0 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
1st Optimal
Pros
- ✓Offers both semaglutide and tirzepatide with injectable and oral formats
- ✓Functional-medicine approach with at-home labs and blood-work interpretation
- ✓Unlimited coaching and ongoing support included
- ✓No long-term contracts
- ✓Board-certified doctors and nurse practitioners referenced
Cons
- ✗No public monthly pricing disclosed
- ✗No published state availability list
- ✗Compounded vs branded sourcing not clarified on site
- ✗Pricing only revealed after quiz or consultation
MyFastRx
Pros
- ✓Aggressive 12-month bundle pricing — $99/mo semaglutide, $149/mo tirzepatide
- ✓LegitScript certified
- ✓All doses priced the same — no cost escalation as you titrate up
- ✓First-month promo discount lowers the trial barrier
Cons
- ✗States served not disclosed — only 'multiple states' / 'licensed U.S. providers'
- ✗Corporate address and medical director not published
- ✗Pharmacy partner not named — only 'state-licensed pharmacies'
- ✗Cash-pay only — no insurance billing
- ✗Bundle savings require a large upfront commitment (12 months billed at once)
Our Verdict
MyFastRx edges out 1st Optimal with a higher overall score of 7.0/10 and is particularly strong for Cash-pay patients comfortable with 12-month upfront billing for the lowest compounded-GLP-1 monthly rate.. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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