1st Optimal vs Heva Health
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine programHeva Health
Best for concierge GLP-1 with a 91-biomarker lab panel and hormone optimizationStarting at $149/mo
Side-by-Side Comparison
| Feature | 1st Optimal | Heva Health |
|---|---|---|
| Overall Score | 6.7/10 | ✓7.2/10 |
| Starting Price | — | $149/mo |
| Editorial Rating | 3.4 ★ /5 | ✓3.6 ★ /5 |
| Features | ✓8 features | 7 features |
| States Available | 0 | 0 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
1st Optimal
Pros
- ✓Offers both semaglutide and tirzepatide with injectable and oral formats
- ✓Functional-medicine approach with at-home labs and blood-work interpretation
- ✓Unlimited coaching and ongoing support included
- ✓No long-term contracts
- ✓Board-certified doctors and nurse practitioners referenced
Cons
- ✗No public monthly pricing disclosed
- ✗No published state availability list
- ✗Compounded vs branded sourcing not clarified on site
- ✗Pricing only revealed after quiz or consultation
Heva Health
Pros
- ✓$149/mo entry pricing for compounded GLP-1 is competitive
- ✓LegitScript Certified
- ✓Claims licensure in all 50 states
- ✓Comprehensive 91-biomarker lab panel bundled — a differentiator vs compounded-GLP-1-only peers
- ✓Concierge care plus HRT/TRT alongside GLP-1 for an integrated longevity stack
- ✓No separate consultation fee
Cons
- ✗Tirzepatide pricing not shown — only the generic $149/mo weight-loss entry
- ✗Legal entity name and state of incorporation not disclosed
- ✗Partner pharmacy not named
- ✗Per-state availability not listed despite the all-50-states claim
- ✗Brand-name GLP-1 options (Wegovy/Zepbound/Mounjaro/Ozempic/Foundayo) not addressed
- ✗Unclear whether the lab panel is bundled with the entry tier or costs extra
Our Verdict
Heva Health edges out 1st Optimal with a higher overall score of 7.2/10 and is particularly strong for concierge GLP-1 with a 91-biomarker lab panel and hormone optimization. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.