1st Optimal vs Hers
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
1st Optimal and Hers are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $149/mo, and Hers edges ahead overall (7.5 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Hers
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149. Microdosing tier.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149. Flagged 'New' on the page.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149. Flagged 'New' on the page.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149. Note this is a different, far dearer tier than the $299 Zepbound Vial/KwikPen — do not conflate them.
Medication only. A Hers Weight Loss Membership is MANDATORY on top — $39 the first month, then $149/mo — and Hers states plainly that 'Medication is not available without a membership', so the all-in standing cost is this figure plus $149. Distinct from the $299 Zepbound Vial and KwikPen rows above.
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 500+ providers' prices on their own sites and email you when tracked prices move.
What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Hers
What the monthly price covers
Medication
Included
Provider visits
Billed separately
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Billed separately
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Hers
7.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Hers |
|---|---|---|
| Starting Price | ✓$99/mo | $149/mo |
| Features | ✓8 features | 2 features |
| States Available | Not disclosed | 50 |
| Compounded | — | — |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Hers
Women-focused telehealth brand from Hims and Hers. As of August 2026 it sells only brand-name GLP-1s — Wegovy, Ozempic, Zepbound, Mounjaro and the new Foundayo pill, from $149/mo for medication — and no longer offers a compounded option. Every price excludes a mandatory Hers Weight Loss Membership at $149/mo after a $39 first month.
Read our full Hers review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Hers
What we like
- Compounded GLP-1 access
Watch-outs
- Every advertised price is medication-only — a mandatory $149/mo membership is billed separately on top
- No compounded option; brand-name medication only, so the cheapest all-in route is $298/mo
- Limited public information on program details
Our Verdict
Hers edges out 1st Optimal with a higher overall score of 7.5/10 and is particularly strong for mainstream telehealth GLP-1 access. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Hers if…
You want mainstream telehealth GLP-1 access and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $88/mo
Get started →MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →1st Optimal vs Hers: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring 1st Optimal and Hers head-to-heads in the same category.
- 1st Optimal vs Amazon One Medical
- 1st Optimal vs Vytora Health
- 1st Optimal vs Collective
- Hers vs CoreAge Rx
- Hers vs EverSlim
- Hers vs Found
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.