1st Optimal vs Evergreen Telehealth
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Evergreen Telehealth
Best for: readers tracking a peptide-led GLP-1 program before it opens to members
Visit Evergreen Telehealth →1st Optimal and Evergreen Telehealth are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts at $99/mo, and Evergreen Telehealth edges ahead overall (6.9 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Evergreen Telehealth
Pricing not publicly listed.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Evergreen Telehealth
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Evergreen Telehealth
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Evergreen Telehealth |
|---|---|---|
| Starting Price | $99/mo | — |
| Features | ✓8 features | 4 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | — |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Evergreen Telehealth
Evergreen Telehealth is a peptide-led wellness brand whose Evergreen Lean program pairs compounded GLP-1s — tirzepatide or semaglutide — with MOTS-c, sermorelin, LDN and B12 protocols. Two named clinicians lead it: a residency-trained compounding pharmacist and a family-practice physician. Memberships are not open yet: every button on the site joins a waitlist, with enrollment stated to begin in September 2026, so no GLP-1 price is purchasable today.
Read our full Evergreen Telehealth review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Evergreen Telehealth
What we like
- Names its clinical leadership with credentials — a PharmD compounding specialist and a board-certified family physician.
- Publishes a LegitScript seal ID that resolves against LegitScript's CDN, though the badge itself links only to a generic lookup.
- States that dispensing pharmacies are PCAB, NABP and LegitScript certified.
- Publishes its plan terms up front, including which commitments are paid upfront.
- Pairs GLP-1s with a named peptide menu rather than leaving the protocol vague.
Watch-outs
- Nothing can be bought yet — every call to action joins a waitlist, with memberships stated to open in September 2026.
- No GLP-1 price is published; the only figure is "Starting at $159/month" for the program, and pricing "varies by medication".
- Month-to-month plans carry a two-month minimum, so the cheapest way in is not a single month.
- The 6- and 12-month plans are paid upfront, not billed monthly at the advertised rate.
- Fees are "final and non-refundable once an order has been processed", with only narrow exceptions.
- No dispensing pharmacy is named — only the accreditations they hold.
- The site says its pharmacy network "covers all 50 states" while its own FAQ says availability "varies by state and by product".
- Support is email only; no phone number or published hours.
Our Verdict
Evergreen Telehealth edges out 1st Optimal with a higher overall score of 6.9/10 and is particularly strong for readers tracking a peptide-led GLP-1 program before it opens to members. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Evergreen Telehealth if…
You want readers tracking a peptide-led GLP-1 program before it opens to members.
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Mainstream telehealth GLP-1 access
From $149.25/mo
Get started →1st Optimal vs Evergreen Telehealth: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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