1st Optimal vs EOS Health
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine programEOS Health
Best for people who want compounded GLP-1 from a provider that openly names its clinical and pharmacy partnersStarting at $199/mo
Side-by-Side Comparison
| Feature | 1st Optimal | EOS Health |
|---|---|---|
| Overall Score | 6.7/10 | ✓7.7/10 |
| Starting Price | — | $199/mo |
| Editorial Rating | 3.4 ★ /5 | ✓3.9 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓40 |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
EOS Health
What we like
- Unusually transparent: publicly names its clinical partner (Arora Health & Aesthetics, LLC) and pharmacy partner (F&F Pharmacies dba Jungle Jim's)
- Competitive compounded pricing from $199/mo semaglutide and $289/mo tirzepatide, plus $100 off the first prescription with code WELCOME100
- Multiple compounded formulas (semaglutide, semaglutide+glycine, semaglutide+B12, tirzepatide) and optional 130+ biomarker lab add-ons
- Free expedited shipping, no insurance required, 10-minute intake, and an ongoing care team via patient portal
Watch-outs
- Available in only 40 states — not offered in CA, NV, NJ, SC, TX, MA, MS, NH, WV, or DE (pharmacy partner is unlicensed there)
- Headline prices are 'best rate' figures; standard monthly plans may cost more than the quarterly-plan rate shown
- Compounded medication only — no brand-name or insurance-covered GLP-1 path
- Pharmacy partner's page notes it 'cannot dispense sterile compounds,' which is worth confirming for injectable GLP-1 fulfillment
Our Verdict
EOS Health edges out 1st Optimal with a higher overall score of 7.7/10 and is particularly strong for people who want compounded GLP-1 from a provider that openly names its clinical and pharmacy partners. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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