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1st Optimal vs Embody

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Embody logo

Embody

7.8
★★★3.9/5

Best for: low flat-rate compounded GLP-1 pricing at every dose

Visit Embody

1st Optimal and Embody are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Embody starts lower at $79/mo versus $99/mo, and Embody edges ahead overall (7.8 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Embody

Injection — flat at every doseCompounded
$79/mo
semaglutide

Checkout: '$79/mo flat forever' (strikethrough $299); bundles $76/$73/$69 per month on 3/6/12-mo. CAVEAT: T&C list price is $199/mo — the $79 depends on the auto-applied SUMMER promo marketed as permanently locked; Trustpilot complaints allege the lock was not always honored.

Injection — flat at every doseCompounded
$129/mo
tirzepatide

Checkout tile 'Flat rate at $119/month (strikethrough $349)'; homepage 'starting at $129/month'; bundles $126/$123/$119 per month.

OralCompounded · oral
$229/mo
semaglutide

New oral semaglutide $229/mo.

Oral / gumCompounded · oral
$329/mo
tirzepatide

Oral tirzepatide $329/mo; gum bundles to $299/mo at 12-month.

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Embody

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Embody

7.8/10

Value25%

6.5A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
6.8

Accessibility10%

6.5A
vs
B
8.5

Support10%

7.4A
vs
B
8.0

Features & Coverage

Feature1st OptimalEmbody
Starting Price$99/mo$79/mo
Features8 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Embody

Embody offers compounded semaglutide and tirzepatide via injection plus a unique compounded oral tirzepatide gum formulation. Aggressive flat-rate pricing with all 50 states and a 24/7 clinician messaging model led by a board-certified internal medicine CMO.

Read our full Embody review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Embody

What we like

  • Among the lowest flat rates in the compounded segment — $79/mo semaglutide and $129/mo tirzepatide injection at every dose
  • Unique compounded oral tirzepatide gum formulation — alternative for patients who prefer not to inject
  • Available in all 50 states with no insurance friction
  • 24/7 unlimited clinician messaging and dose-adjustment support included
  • Medical leadership by Dr. Alan Viglione, board-certified in Internal Medicine

Watch-outs

  • The $79 flat rate relies on an auto-applied promo 'locked forever' — list price in the terms is $199/mo and reviewers allege the lock isn't honored
  • Compounded only — no FDA-approved brand-name Ozempic, Wegovy, Zepbound, or Mounjaro option
  • Pharmacy partners not publicly named — compounding source transparency is limited
  • Compounded oral tirzepatide does not have an FDA-approved counterpart, and oral GLP-1 bioavailability remains an active area of clinical debate

Our Verdict

Winner: Embody

Embody edges out 1st Optimal with a higher overall score of 7.8/10 and is particularly strong for low flat-rate compounded GLP-1 pricing at every dose. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Embody if…

You want low flat-rate compounded GLP-1 pricing at every dose and a starting price around $79/mo.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

1st Optimal vs Embody: FAQ

Embody is cheaper. Its lowest ongoing monthly cash price is $79/mo, compared with $99/mo for 1st Optimal. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Embody scores higher overall at 7.8/10 versus 6.7/10, and is particularly strong for low flat-rate compounded GLP-1 pricing at every dose. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Embody lists availability in 50 states, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor Embody is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Embody is cheaper at $79/mo versus $99/mo at 1st Optimal.

Key terms, explained

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Continue exploring 1st Optimal and Embody head-to-heads in the same category.

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