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1st Optimal vs Eden

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Eden logo

Eden

7.2
★★★3.6/5

Best for: mainstream telehealth GLP-1 access

Visit Eden

1st Optimal and Eden are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $198/mo, and Eden edges ahead overall (7.2 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Eden

StartingCompounded
$198$138/mo
Save 30% right now
semaglutide
StartingCompounded
$298$238/mo
Save 20% right now
tirzepatide

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Eden

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Eden

7.2/10

Value25%

6.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.3

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalEden
Starting Price$99/mo$198/mo
Features8 features3 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNone1 warning

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Eden

Premium telehealth platform with promotional first-month pricing on both semaglutide and tirzepatide.

Read our full Eden review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Eden

What we like

  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Watch-outs

  • Limited public information on program details

Our Verdict

Winner: Eden

Eden edges out 1st Optimal with a higher overall score of 7.2/10 and is particularly strong for mainstream telehealth GLP-1 access. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Eden if…

You want mainstream telehealth GLP-1 access and a starting price around $198/mo.

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8.3

Found

Mainstream telehealth GLP-1 access

7.4

Breeze Meds

Compounded GLP-1 access with named prescribers and 4-pharmacy network

7.4

Telos Rx

Needle-free, microdosed compounded GLP-1 with lab-monitored care

1st Optimal vs Eden: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $198/mo for Eden. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Eden scores higher overall at 7.2/10 versus 6.7/10, and is particularly strong for mainstream telehealth GLP-1 access. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Eden lists availability in 50 states, while 1st Optimal's state list is not publicly listed.
Eden is an affiliate partner (we may earn a commission on sign-ups through our links); 1st Optimal is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $138/mo at Eden.

Key terms, explained

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Continue exploring 1st Optimal and Eden head-to-heads in the same category.

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