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10rx vs ZYP Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
ZYP Medical logo

ZYP Medical

7.1
★★★3.6/5

Best for: Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option

Visit ZYP Medical

10rx and ZYP Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $150/mo, and both land at 7.1/10 overall. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

ZYP Medical

Flat-rate (all doses)Compounded
$150/mo
semaglutide
Injectable (all doses)Compounded
$233/mo
tirzepatide
Oral (all doses)Compounded
$250/mo
tirzepatide

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

ZYP Medical

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

ZYP Medical

7.1/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

7.0A
vs
B
7.0

Trust & Safety15%

5.3A
vs
B
6.8

Accessibility10%

7.5A
vs
B
6.5

Support10%

6.4A
vs
B
7.4

Features & Coverage

Feature10rxZYP Medical
Starting Price$99.67/mo$150/mo
Features8 features6 features
States AvailableNot disclosed6
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About ZYP Medical

ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states. Compounded semaglutide starts at $150/month, injectable tirzepatide at $233/month, and oral tirzepatide at $250/month, with all prices including medication and shipping. An initial one-hour consultation is $50, and there are no membership fees. Care is provided by Joshua Peterson, FNP-C, a board-certified family nurse practitioner. The company discloses that compounded medications are not FDA-approved and recommends FDA-approved brands as first-line treatment.

Read our full ZYP Medical review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

ZYP Medical

What we like

  • Transparent flat-rate pricing including medication and shipping with no hidden fees
  • Low $50 initial one-hour consultation
  • Offers both injectable and oral tirzepatide options
  • No membership fees and pricing decreases as treatment progresses
  • Care from a board-certified family nurse practitioner
  • Discreet 2-day shipping

Watch-outs

  • Compounded medications are not FDA-approved
  • Available in only six states (NE, IA, SD, KS, CO, AZ)
  • Cash-pay only; no insurance noted
  • No named compounding pharmacy partner disclosed
  • No LegitScript certification shown on site

Our Verdict

Both 10rx and ZYP Medical score equally well overall — the right choice depends on your priorities.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose ZYP Medical if…

You want Men in NE, IA, SD, KS, CO, or AZ wanting low-cost compounded GLP-1s with oral option and a starting price around $150/mo.

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8.0

Sesame Care

Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

10rx vs ZYP Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.