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10rx vs Vyvron

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Vyvron logo

Vyvron

6.3
★★★☆☆3.2/5

Best for: a locked founding rate from a platform that names its clinical partner and holds a real LegitScript seal

Visit Vyvron

10rx and Vyvron are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $179/mo, and 10rx edges ahead overall (7.1 vs 6.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Vyvron

Lower tier, billed every 4 weeks (13 charges a year, not 12)Compounded
$179$149/mo
Save 17% right now

Founding-member rate of $149 per 4 weeks is locked for the life of the membership; the standing rate is $179. Vyvron does not state which medication this tier buys.

Higher tier, billed every 4 weeks (13 charges a year, not 12)Compounded
$249$199/mo
Save 20% right now

Founding-member rate of $199 per 4 weeks is locked for the life of the membership; the standing rate is $249. Vyvron does not state which medication this tier buys.

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Vyvron

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Vyvron

6.3/10

Value25%

8.5A
vs
B
6.5

Effectiveness25%

7.0A
vs
B
6.5

User Experience15%

7.0A
vs
B
6.5

Trust & Safety15%

5.3A
vs
B
6.0

Accessibility10%

7.5A
vs
B
5.5

Support10%

6.4A
vs
B
6.0

Features & Coverage

Feature10rxVyvron
Starting Price$99.67/mo$179/mo
Features8 features5 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Vyvron

Vyvron is a Wyoming-registered telehealth access platform for online weight-management evaluation. It is explicit that it is not a medical practice or pharmacy: clinical and pharmacy services run through OpenLoop Health and its affiliated professional entities. Membership is sold at two tiers, currently $149 and $199 per four weeks under a founding-member rate that reverts to $179 and $249, and the site carries a verified LegitScript certification. Vyvron names semaglutide and tirzepatide as possible options but never ties either drug to a published price.

Read our full Vyvron review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Vyvron

What we like

  • Carries a genuine LegitScript seal (ID 50305996) that resolves on LegitScript's own asset host, with the domain named in the badge.
  • Names OpenLoop Health as the clinical and pharmacy partner, and links its telehealth consent to OpenLoop directly.
  • Unusually blunt disclosures: states plainly it is not a medical practice or pharmacy and that compounded drugs are not FDA-approved.
  • No cancellation fees, and the founding rate is contractually locked for as long as the membership runs.

Watch-outs

  • No price is tied to a medication anywhere, so you cannot tell which tier buys semaglutide and which buys tirzepatide before paying.
  • Billed every four weeks, which is 13 charges a year rather than 12, so the true annual cost is a month higher than it looks.
  • "100 of 100 founding spots left" appears twice on the page and does not count down, so the scarcity framing is not real.
  • Registered at 30 N Gould St, Sheridan WY, a mass registered-agent address, and no state coverage list is published.

Our Verdict

Winner: 10rx

10rx edges out Vyvron with a higher overall score of 7.1/10 and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Vyvron remains a solid alternative, especially if you're looking for a locked founding rate from a platform that names its clinical partner and holds a real LegitScript seal.

Choose 10rx if…

You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Vyvron if…

You want a locked founding rate from a platform that names its clinical partner and holds a real LegitScript seal and a starting price around $179/mo.

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10rx vs Vyvron: FAQ

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