10rx vs Vyora Wellness
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →
Vyora Wellness
Best for: patients wanting coaching-inclusive compounded GLP-1 programs
Visit Vyora Wellness →10rx and Vyora Wellness are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $299/mo, and 10rx edges ahead overall (7.1 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Vyora Wellness
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Vyora Wellness
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Vyora Wellness
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Vyora Wellness |
|---|---|---|
| Starting Price | ✓$99.67/mo | $299/mo |
| Features | ✓8 features | 5 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Vyora Wellness
Vyora Wellness offers compounded semaglutide ($299/mo) and compounded tirzepatide ($399/mo) as 4-week subscription plans. LegitScript certified. Price includes GLP-1 nutritional guidance, 24/7 coaching, and community access. BMI 25+ required.
Read our full Vyora Wellness review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Vyora Wellness
What we like
- LegitScript certified
- Price includes nutritional guidance, 24/7 coaching, and community access
- Both semaglutide and tirzepatide available
- BMI 25+ eligibility threshold (lower than some competitors)
Watch-outs
- State availability not publicly disclosed
- Pricing is above average ($299–$399/mo) compared to competitors
- Compounded only — no brand-name options
- Broader platform (metabolic, longevity, topical products)
Our Verdict
10rx edges out Vyora Wellness with a higher overall score of 7.1/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Vyora Wellness remains a solid alternative, especially if you're looking for patients wanting coaching-inclusive compounded GLP-1 programs.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Vyora Wellness if…
You want patients wanting coaching-inclusive compounded GLP-1 programs and a starting price around $299/mo.
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Direct Meds
Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →10rx vs Vyora Wellness: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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