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10rx vs Vital Step

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★★☆3.6/5

Best for: low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx →
VS
Vital Step logo

Vital Step

6.3
★★★☆☆3.2/5

Best for: people who want compounded semaglutide or tirzepatide as an injection or a daily tablet, month to month

Visit Vital Step →

10rx and Vital Step are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $296/mo, and 10rx edges ahead overall (7.1 vs 6.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$96.67/mo
semaglutide
Injectablecompounded injection
$149.67/mo
tirzepatide

Vital Step

Month-to-month plan, weekly injection, auto-renews monthlyCompounded
$296$179/mo
Save 40% right now
semaglutide

$179 first month, then $296/mo. 3, 6 and 12-month supplies are billed upfront: $717, $1,326 and $2,592

Month-to-month plan, daily dissolving tablet, auto-renews monthlyCompounded
$296$179/mo
Save 40% right now
semaglutide

$179 first month, then $296/mo. 3, 6 and 12-month supplies are billed upfront: $717, $1,326 and $2,592

Month-to-month plan, weekly injection, auto-renews monthlyCompounded
$396$279/mo
Save 30% right now
tirzepatide

$279 first month, then $396/mo. 3, 6 and 12-month supplies are billed upfront: $1,068, $2,022 and $3,918

Month-to-month plan, daily dissolving tablet, auto-renews monthlyCompounded
$396$279/mo
Save 30% right now
tirzepatide

$279 first month, then $396/mo. 3, 6 and 12-month supplies are billed upfront: $1,068, $2,022 and $3,918

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Vital Step

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Vital Step

6.3/10

Value25%

8.5A
vs
B
5.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
5.5

Trust & Safety15%

5.3A
vs
B
5.5

Accessibility10%

7.5A
vs
B
7.0

Support10%

6.4A
vs
B
6.0

Features & Coverage

Feature10rxVital Step
Starting Price✓$96.67/mo$296/mo
Features✓8 features6 features
States AvailableNot disclosedNot disclosed
Compounded—✓ Yes
Brand Name——
FSA/HSA Accepted—✓ Yes
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Vital Step

Vital Step is a Nevada telehealth company that sells compounded semaglutide and tirzepatide as weekly injections or daily dissolving tablets, prescribed through the Dr. TelX medical group. Month-to-month plans renew at $296 a month for semaglutide and $396 for tirzepatide after a discounted first month. The advertised $161 and $198 figures are the first month of a 6-month plan billed upfront.

Read our full Vital Step review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to pin down
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Vital Step

What we like

  • Offers both semaglutide and tirzepatide, each as a weekly injection or a daily dissolving tablet
  • Names its medical group (Dr. TelX) in its terms of service
  • Monthly price is described as covering the provider review, dosing guidance, ongoing support and the medication
  • Free shipping is advertised on the home page and product pages
  • A month-to-month plan is available with no prepay requirement
  • Says HSA and FSA funds can be used for eligible expenses

Watch-outs

  • The "as low as $161" and "$198" prices are the first month of 6-month plans charged upfront ($1,326 and $2,022)
  • After a discounted first month, month-to-month plans renew at $296 for semaglutide and $396 for tirzepatide
  • Plan prices appear only after you enter an email address in the intake
  • Strict no-refund policy: fees are not refundable in whole or in part, and partial subscription periods are not refunded
  • The site lists all 50 states, but its terms exclude Alaska, Arkansas, Louisiana, New Hampshire, Oregon, South Carolina, West Virginia and DC
  • The dispensing pharmacy is not named; product pages call the pharmacies "FDA approved"
  • The LegitScript badge links to a generic lookup page, and no certification record could be confirmed
  • Two home-page testimonials share identical wording, and no independent reviews exist yet

Our Verdict

Winner: 10rx

10rx edges out Vital Step with a higher overall score of 7.1/10 and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Vital Step remains a solid alternative, especially if you're looking for people who want compounded semaglutide or tirzepatide as an injection or a daily tablet, month to month.

Choose 10rx if…

You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.

Choose Vital Step if…

You want people who want compounded semaglutide or tirzepatide as an injection or a daily tablet, month to month and a starting price around $296/mo.

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10rx vs Vital Step: FAQ

10rx is cheaper. Its lowest ongoing monthly cash price is $96.67/mo, compared with $296/mo for Vital Step. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
10rx scores higher overall at 7.1/10 versus 6.3/10, and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. That said, Vital Step is a better fit if you want people who want compounded semaglutide or tirzepatide as an injection or a daily tablet, month to month.
Neither 10rx nor Vital Step publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 10rx nor Vital Step is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 10rx is cheaper at $96.67/mo versus $179/mo at Vital Step.

Key terms, explained

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Continue exploring 10rx and Vital Step head-to-heads in the same category.

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