10rx vs Trellis Vitality
An in-depth comparison of two leading GLP-1 Providers
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Trellis Vitality
Best for: body-composition tracking and flat per-dose pricing without a membership fee
Visit Trellis Vitality →10rx and Trellis Vitality are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $150/mo, and Trellis Vitality edges ahead overall (7.5 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Trellis Vitality
Per-month rate falls on longer plans: $150 monthly, $140 on 3 months, $133 on 6 months. All dosages cost the same.
Per-month rate falls on longer plans: $199 monthly, $189 on 3 months, $179 on 6 months. All dosages cost the same.
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Trellis Vitality
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Trellis Vitality
7.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Trellis Vitality |
|---|---|---|
| Starting Price | ✓$99.67/mo | $150/mo |
| Features | ✓8 features | 7 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Trellis Vitality
Trellis Vitality is an online longevity clinic that frames weight loss around body composition rather than scale weight. Compounded semaglutide starts at $150 a month and tirzepatide at $199, with every dose priced the same and no membership or consult fee layered on top. The programme pairs GLP-1s with at-home biomarker panels, a 90-day re-test, and muscle-preserving options such as tesamorelin and glycine formulations. Trellis is a care-coordination company; prescribing is done by the Arora Health provider network and dispensing by Houston pharmacy VialsRX.
Read our full Trellis Vitality review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Trellis Vitality
What we like
- Names both its pharmacy (VialsRX, Houston TX) and its prescribing network, with a street address and phone number for the pharmacy.
- All dosages cost the same, and there is no membership fee or consult charge on top of the monthly price.
- Frames the programme around body composition, with at-home biomarker panels and a 90-day re-test rather than scale weight alone.
- Will review labs from an existing compounded programme and recommend protocol adjustments free of charge.
Watch-outs
- Headline stats (92% biomarker improvement, $4,000 average annual saving, 3.4 weeks saved) are unsourced and cannot be checked.
- The "4.7 / 5 · 5,000+ current patients" rating names no review platform, so it cannot be verified against a public record.
- Prescribing runs through the Arora Health network, which several unrelated telehealth brands also use, so the clinical layer is not exclusive.
- Refund eligibility is decided per order rather than by a stated policy, so outcomes are discretionary.
Our Verdict
Trellis Vitality edges out 10rx with a higher overall score of 7.5/10 and is particularly strong for body-composition tracking and flat per-dose pricing without a membership fee. 10rx remains a solid alternative, especially if you're looking for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Trellis Vitality if…
You want body-composition tracking and flat per-dose pricing without a membership fee and a starting price around $150/mo.
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Oral-lozenge compounded GLP-1 access
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Mainstream telehealth GLP-1 access
From $146/mo
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Best overall value
From $135/mo
Get started →10rx vs Trellis Vitality: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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