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10rx vs Science & Co

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Science & Co logo

Science & Co

7.4
★★★3.7/5

Best for: the cheapest month-to-month compounded rate, if you accept a contact gate

Visit Science & Co

10rx and Science & Co are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Science & Co starts lower at $89/mo versus $96.67/mo, and Science & Co edges ahead overall (7.4 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$96.67/mo
semaglutide
Injectablecompounded injection
$149.67/mo
tirzepatide

Science & Co

Once-weekly compounded injection, month-to-month plan (renews every 30 days)Compounded
$89/mo
semaglutide

Month-to-month rate from the plan table. Prepay tiers: 3-month $250 ($83/mo), 6-month $486 ($81/mo), 12-month $948 ($79/mo) — each billed in one upfront charge.

Once-weekly compounded injection, month-to-month plan (renews every 30 days)Compounded
$139/mo
tirzepatide

Month-to-month rate from the plan table. Prepay tiers: 3-month $399 ($133/mo), 6-month $774 ($129/mo), 12-month $1,500 ($125/mo) — each billed in one upfront charge.

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Science & Co

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Science & Co

7.4/10

Value25%

8.5A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
6.5

Trust & Safety15%

5.3A
vs
B
5.5

Accessibility10%

7.5A
vs
B
7.5

Support10%

6.4A
vs
B
7.5

Features & Coverage

Feature10rxScience & Co
Starting Price$96.67/mo$89/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Science & Co

Science & Co is a cash-pay telehealth service selling compounded semaglutide from $89/mo and compounded tirzepatide from $139/mo month-to-month, flat at every dose, with free overnight shipping and no membership fee. Those are among the lowest month-to-month GLP-1 rates we track, but the marketing site quotes only '$2 a day' and a 12-month rate buried in a collapsed FAQ; the plan table with the real month-to-month price appears only after you hand over your name, email, phone and state.

Read our full Science & Co review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Science & Co

What we like

  • $89/mo month-to-month for compounded semaglutide is at the bottom of the range we track
  • Flat at every dose — 'You pay the same whether you are on your starting dose or your highest one'
  • Free overnight shipping, no membership fee and no consultation fee
  • Prepay tiers are cheaper per month and are shown side by side with the monthly rate, not instead of it
  • Published phone line and email, both staffed as 24/7 messaging with the care team
  • HSA and FSA eligible
  • Cancel any time before the next renewal from the patient portal

Watch-outs

  • The marketing site quotes only a per-day figure and the 12-month rate; the plan table appears only after you give your name, email, phone and state
  • Trustpilot has removed this company's profile as against its guidelines, while the site advertises '4.8 · 1,200+ member reviews'
  • The LegitScript badge is a self-hosted image on the company's own CDN, not a LegitScript-served seal, and its lookup shows no record
  • The monthly plan 'renews every 30 days' — 13 charges in a year, not 12
  • The advertised '$79 a month' is the 12-month tier: a single $948 charge up front
  • The compounding pharmacy is never named; the company states it is 'not a 503A or 503B compounding facility'
  • Marketing consent to email and text arrives pre-checked on the contact step
  • Named before/after testimonials repeat across pages, and the '15% lost on average' figure is labeled illustrative

Our Verdict

Winner: Science & Co

Science & Co edges out 10rx with a higher overall score of 7.4/10 and is particularly strong for the cheapest month-to-month compounded rate, if you accept a contact gate. 10rx remains a solid alternative, especially if you're looking for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.

Choose Science & Co if…

You want the cheapest month-to-month compounded rate, if you accept a contact gate and a starting price around $89/mo.

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8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

10rx vs Science & Co: FAQ

Science & Co is cheaper. Its lowest ongoing monthly cash price is $89/mo, compared with $96.67/mo for 10rx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Science & Co scores higher overall at 7.4/10 versus 7.1/10, and is particularly strong for the cheapest month-to-month compounded rate, if you accept a contact gate. That said, 10rx is a better fit if you want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Neither 10rx nor Science & Co publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 10rx nor Science & Co is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Science & Co is cheaper at $89/mo versus $96.67/mo at 10rx.

Key terms, explained

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Continue exploring 10rx and Science & Co head-to-heads in the same category.

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